Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GALK1 | P51570 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL313390 | 0.88 | ALDH1A1 (0.46) | ALDH1A1HSD17B10TDP1AKR1B1CASP1 | |
| SCHEMBL15879481 | 0.82 | PTGS2 (0.48) | ALDH1A1HSD17B10TDP1MEN1APAF1 | |
| SCHEMBL8765653 | 0.81 | PTPRC (0.46) | ALDH1A1HSD17B10TDP1RAB9AKMT2A | |
| SCHEMBL7127239 | 0.79 | ALDH1A1 (0.48) | ALDH1A1HSD17B10TDP1MEN1APAF1 | |
| SCHEMBL31194215 | 0.78 | PTGS2 (0.46) | ALDH1A1HSD17B10TDP1MEN1APAF1 | |
| SCHEMBL8196670 | 0.78 | ALDH1A1 (0.61) | ALDH1A1HSD17B10TDP1NPC1RAB9A | |
| SCHEMBL5679414 | 0.77 | NPC1 (0.44) | ALDH1A1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL29118492 | 0.76 | ALDH1A1 (0.43) | ALDH1A1HSD17B10TDP1MEN1APAF1 | |
| SCHEMBL30076027 | 0.74 | MEN1 (0.46) | MEN1APAF1NPC1LMNAMAPT | |
| SCHEMBL4202592 | 0.74 | PTGS2 (0.55) | ALDH1A1MAPTRAB9APTGS2FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004065-B1 | METHOD FOR PRODUCING PYRIDAZINE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2017-10-18 | — | — | EP | disclosed |
| US-9732042-B2 | Method for producing pyridazine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-15 | — | — | US | disclosed |
| US-20160090363-A1 | METHOD FOR PRODUCING PYRIDAZINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160090363-A1 | METHOD FOR PRODUCING PYRIDAZINE COMPOUND | PLP2, PNPO, CBR3 | ALDH1A1 1585/4885HSD17B10 1783/4885TDP1 3484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.