Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | EDNRB | P24530 | 4/20 | 0.42 |
| ▸ | EDNRA | P25101 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15879481 | 0.93 | PTGS2 (0.48) | ALDH1A1HSD17B10TDP1PTGS2AKR1B1 | |
| SCHEMBL31194215 | 0.90 | PTGS2 (0.46) | ALDH1A1HSD17B10TDP1PTGS2AKR1B1 | |
| SCHEMBL8196670 | 0.89 | ALDH1A1 (0.61) | ALDH1A1HSD17B10TDP1PTGS2AKR1B1 | |
| SCHEMBL17628496 | 0.88 | ALDH1A1 (0.40) | ALDH1A1HSD17B10TDP1PTGS2AKR1B1 | |
| SCHEMBL7127239 | 0.85 | ALDH1A1 (0.48) | ALDH1A1HSD17B10TDP1PTGS2MAPK1 | |
| SCHEMBL4202592 | 0.85 | PTGS2 (0.55) | ALDH1A1PTGS2HPGDFBP1PTGS1 | |
| SCHEMBL2008147 | 0.84 | PTGS2 (0.53) | ALDH1A1PTGS2PTGS1 | |
| SCHEMBL2007711 | 0.84 | PTPRC (0.44) | ALDH1A1HSD17B10TDP1PTGS2EDNRB | |
| SCHEMBL7127244 | 0.84 | ALDH1A1 (0.40) | ALDH1A1HSD17B10TDP1PTGS2AKR1B1 | |
| SCHEMBL5682823 | 0.84 | CA12 (0.42) | ALDH1A1HSD17B10TDP1PTGS2EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 298 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120020125-A | Preparation method of biphenyl sulfide-containing compound | 沈阳中化农药化工研发有限公司 | 2025-05-20 | — | — | CN | claimed |
| CN-108191746-B | Hydroxypyridones compound and preparation method and application thereof | 暨南大学 | 2020-06-16 | — | — | CN | claimed |
| US-12516028-B2 | Triazinanes possessing thiosulfonate end-groups and methods of making them | FLEXSYS IP HOLDINGS, LLC (US) | 2026-01-06 | — | — | US | disclosed |
| EP-4229045-B1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | BROAD INST INC (US) | 2025-11-12 | — | — | EP | disclosed |
| WO-2025224168-A1 | ARYL SULFONE AND SULFANONE DERIVATIVES AS OREXIN RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-10-30 | — | — | WO | disclosed |
| US-12378254-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2025-08-05 | — | — | US | disclosed |
| CN-120020125-A | Preparation method of biphenyl sulfide-containing compound | 沈阳中化农药化工研发有限公司 | 2025-05-20 | — | — | CN | disclosed |
| CN-119264303-A | Pendant group functionalized fluorine-containing polymer, preparation method of fluorine-containing polymer, ion exchange membrane and application | 佛山绿动氢能科技有限公司 | 2025-01-07 | — | — | CN | disclosed |
| WO-2024205303-A1 | NOVEL AMIDE-BASED COMPOUND AND COMPOSITION COMPRISING SAME | (주)아모레퍼시픽 | 2024-10-03 | — | — | WO | disclosed |
| US-20240287048-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | BAYER AKTIENGESELLSCHAFT (DE) | 2024-08-29 | — | — | US | disclosed |
| US-20240109901-A1 | DISUBSTITUTED OCTAHYDROPYRROLO[3,4-C]PYRROLES AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-04-04 | — | — | US | disclosed |
| US-4835312-A | Production process of N-substituted amide compounds | MITSUI CHEMICALS, INCORPORATED (JP) | 1989-05-30 | — | — | US | disclosed |
| US-4710509-A | IMIDAZOLE AND TRIAZOLE DERIVATIVES; FUNGICIDES | NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) | 1987-12-01 | — | — | US | disclosed |
| EP-0173918-A2 | Substituted phenylsulfonyl azoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-03-12 | — | — | EP | disclosed |
| EP-0138139-A2 | Process for the preparation of substituted benzenesulfonyl chloride | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-04-24 | — | — | EP | disclosed |
| EP-0027906-B1 | PROCESS FOR PREPARING SULPHON AMIDES | BAYER AG (DE) | 1983-05-25 | — | — | EP | disclosed |
| EP-0027906-A1 | Process for preparing sulphon amides | BAYER AG (DE) | 1981-05-06 | — | — | EP | disclosed |
| US-4060549-A | Process for preparing sulfonic acid fluorides | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-29 | — | — | US | disclosed |
| US-4007058-A | Matrix construction for fuel cells | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1977-02-08 | — | — | US | disclosed |
| US-3966703-A | Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240287048-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | KAT6A, KAT6B, KAT2A | ALDH1A1 1125/4885HSD17B10 566/4885TDP1 2741/4885 |
| US-20240109901-A1 | DISUBSTITUTED OCTAHYDROPYRROLO[3,4-C]PYRROLES AS OREXIN RECEPTOR MODULATORS | HCRTR2, HCRTR1, OXTR | ALDH1A1 3132/4885HSD17B10 3775/4885TDP1 3692/4885 |
| US-12378254-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | HCRTR2, HCRTR1, OXTR | ALDH1A1 3132/4885HSD17B10 3775/4885TDP1 3692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.