SCHEMBL7127239

SCHEMBL7127239

O=S(=O)(Cl)c1ccccc1-c1ccccc1S(=O)(=O)Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
HSD17B10 Q99714 1/20 0.48
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
CDC25B P30305 1/20 0.43
IDO1 P14902 1/20 0.42
DNMT1 P26358 1/20 0.42
DNMT3L Q9UJW3 1/20 0.42
DNMT3A Q9Y6K1 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
APAF1 O14727 2/20 0.41
TDP2 O95551 2/20 0.41
S100A4 P26447 2/20 0.41
PLCG1 P19174 2/20 0.41
NPC1 O15118 2/20 0.41
LMNA P02545 2/20 0.41
MAPT P10636 2/20 0.41
MAPK1 P28482 2/20 0.41
HTT P42858 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6294222 0.87 CA1 (0.48) ALDH1A1TDP1HSD17B10MEN1KMT2A
SCHEMBL6291104 0.87 ALDH1A1 (0.43) ALDH1A1TDP1HSD17B10MEN1KMT2A
SCHEMBL5679063 0.87 CA12 (0.43) ALDH1A1TDP1HSD17B10MEN1KMT2A
SCHEMBL313390 0.85 ALDH1A1 (0.46) ALDH1A1TDP1HSD17B10MAPK1PTGS1
SCHEMBL250199 0.85 ALDH1A1 (0.55) ALDH1A1TDP1HSD17B10MEN1KMT2A
SCHEMBL3909203 0.85 CA1 (0.52) MEN1KMT2ADNMT1KDM4EGAA
SCHEMBL31194215 0.85 PTGS2 (0.46) ALDH1A1TDP1HSD17B10MEN1KMT2A
SCHEMBL8765394 0.83 AHR (0.46) ALDH1A1TDP1HSD17B10IDO1DNMT1
SCHEMBL176933 0.80 KMT2A (0.56) ALDH1A1TDP1HSD17B10MEN1KMT2A
SCHEMBL4202592 0.80 PTGS2 (0.55) ALDH1A1S100A4MAPTRAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119857380-A Gas separation membrane based on metal organic cage and preparation method and application thereof 天津大学 2025-04-22 CN claimed
CN-116510525-B High-flux nanofiltration membrane based on guanidino compound and preparation method and application thereof 天津大学 2023-09-01 CN claimed
CN-116510525-A High-flux nanofiltration membrane based on guanidino compound and preparation method and application thereof 天津大学 2023-08-01 CN claimed
CN-116510525-B High-flux nanofiltration membrane based on guanidino compound and preparation method and application thereof 天津大学 2023-09-01 CN disclosed
CN-116510525-A High-flux nanofiltration membrane based on guanidino compound and preparation method and application thereof 天津大学 2023-08-01 CN disclosed
WO-2017125889-A1 CYCLODEXTRIN BASED POLYMERS, METHODS, COMPOSITIONS AND APPLICATIONS THEREOF ATEN PORUS LIFESCIENCES (IN) 2017-07-27 WO disclosed
US-6670474-B2 Such as bis-1,2-(2-(2,3-epoxypropyl)phenoxy)ethane; chemical intermediates for formation of epoxy resins PEWS R GARTH (US) 2003-12-30 US disclosed
US-20020151731-A1 Novel epoxide derivatives of allylarylphenols PEWS R GARTH (US) 2002-10-17 US disclosed
US-4945169-A Novel bis-maleimide compounds containing sulfonate linkages INDSPEC CHEMICAL CORPORATION (US) 1990-07-31 US disclosed
US-4438245-A FOR LIGHT SENSITIVE ELEMENTS FUJI PHOTO FILM CO., LTD. (JP) 1984-03-20 US disclosed
US-4060549-A Process for preparing sulfonic acid fluorides BAYER AKTIENGESELLSCHAFT (DT) 1977-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020151731-A1 Novel epoxide derivatives of allylarylphenols EPHX2, CBR3, CYP4X1 ALDH1A1 578/4885TDP1 4186/4885HSD17B10 404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.