SCHEMBL1762876

SCHEMBL1762876

CCN1CCC(CC(=O)O)CC1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.52
EPHX1 P07099 2/20 0.51
EPHX2 P34913 1/20 0.42
HSD11B1 P28845 2/20 0.42
FFAR4 Q5NUL3 2/20 0.40
SLC6A1 P30531 2/20 0.39
GABRA5 P31644 2/20 0.39
GABRB2 P47870 2/20 0.39
SLC6A12 P48065 2/20 0.39
SLC6A11 P48066 2/20 0.39
SLC6A13 Q9NSD5 2/20 0.39
GABRA1 P14867 1/20 0.39
GABRR1 P24046 1/20 0.39
GABRA4 P48169 1/20 0.39
ANPEP P15144 1/20 0.38
ENPEP Q07075 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3579455 0.98 EPHX1 (0.50) SMN1; SMN2EPHX1EPHX2HSD11B1FFAR4
SCHEMBL7885345 0.88 SMN1; SMN2 (0.44) SMN1; SMN2EPHX1EPHX2HSD11B1SLC6A1
SCHEMBL13934478 0.84 SMN1; SMN2 (0.46) SMN1; SMN2EPHX1EPHX2FFAR4
SCHEMBL13617466 0.83 SMN1; SMN2 (0.52) SMN1; SMN2EPHX1EPHX2HSD11B1
SCHEMBL4822849 0.82 SMN1; SMN2 (0.60) SMN1; SMN2EPHX1EPHX2HSD11B1
SCHEMBL7327464 0.81 EPHX1 (0.47) EPHX1EPHX2
SCHEMBL18930342 0.80 HSD11B1 (0.54) SMN1; SMN2EPHX1EPHX2HSD11B1
SCHEMBL23533551 0.80 KCNH2 (0.51) EPHX1EPHX2
Hydrochloric Acid SCHEMBL23533426 0.80 GNAO1 (0.47) EPHX1EPHX2
SCHEMBL23671734 0.79 SLC6A1 (0.39) FFAR4SLC6A1GABRA5GABRB2SLC6A12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001838-A1 NANOMATERIALS GUIDE THERAPEUTICS LLC (US) 2026-01-01 US disclosed
US-12435035-B2 Nanomaterials GUIDE THERAPEUTICS, LLC (US) 2025-10-07 US disclosed
CN-119684140-A Nanomaterial for the preparation of a nanoparticle 盖德治疗有限责任公司 2025-03-25 CN disclosed
CN-115175894-B Nanomaterial for the preparation of a nanoparticle 盖德治疗有限责任公司 2024-09-06 CN disclosed
US-20240217947-A1 Morpholinylquinazoline Compound, Pharmaceutical compositions thereof and Use Thereof SHANGHAI YINGLI PHARMACEUTICAL CO., LTD (CN) 2024-07-04 US disclosed
US-20230348361-A1 IONIZABLE LIPID COMPOUNDS METIS TECHBIO CO., LTD. (CN) 2023-11-02 US disclosed
US-20230348361-A1 IONIZABLE LIPID COMPOUNDS METIS TECHBIO CO., LTD. (CN) 2023-11-02 US disclosed
US-20230346702-A1 LIPID NANOPARTICLES METIS TECHBIO CO., LTD. (CN) 2023-11-02 US disclosed
US-20230346702-A1 LIPID NANOPARTICLES METIS TECHBIO CO., LTD. (CN) 2023-11-02 US disclosed
WO-2023207102-A1 LIPID NANOPARTICLES Beijing Jitai Pharmaceutical Technology Co., Ltd. (CN) 2023-11-02 WO disclosed
EP-0511222-A1 DISUBSTITUTED PIPERIDINES AND PYRROLIDINES AS ANTICHOLINERGIC AGENTS. PFIZER LTD (GB) 1992-11-04 EP disclosed
US-5112825-A Antirhinoviral heteroamine-substituted pyridazines JANSSEN PHARMACEUTICA N.V. (BE) 1992-05-12 US disclosed
US-5100893-A Viricides, effective against picorna virus, durability JANSSEN PHARMACEUTICA N.V. (BE) 1992-03-31 US disclosed
WO-1991010651-A1 ANTICHOLINERGIC AGENTS PFIZER LIMITED (GB) 1991-07-25 WO disclosed
EP-0435381-A1 Antipicornaviral pyridazinamines JANSSEN PHARMACEUTICA N.V. (BE) 1991-07-03 EP disclosed
US-4983614-A ANTISPASMODIC, ANTIALLERGENIC AND ANTIHISTAMINE AGENTS LES LABORATOIRES MERAM (FR) 1991-01-08 US disclosed
EP-0398427-A1 Antirhinoviral pyridazinamines JANSSEN PHARMACEUTICA N.V. (BE) 1990-11-22 EP disclosed
EP-0037713-B1 NOVEL 1,3-DIHYDRO-1-((1-PIPERIDINYL)ALKYL)-2H-BENZIMIDAZOL-2-ONE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 1984-02-08 EP disclosed
EP-0037713-A1 Novel 1,3-dihydro-1-((1-piperidinyl)alkyl)-2H-benzimidazol-2-one derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1981-10-14 EP disclosed
US-4254127-A ANTIEMETIC, NEUROLIPTIC AND ANTICONGESTIVE AGENT JANSSEN PHARMACEUTICA, N.V. (BE) 1981-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240217947-A1 Morpholinylquinazoline Compound, Pharmaceutical compositions thereof and Use Thereof HDAC6, HDAC9, HDAC7 SMN1; SMN2 2725/4885EPHX1 4497/4885EPHX2 4315/4885
US-20260001838-A1 NANOMATERIALS SLC10A1, NPC1L1, FABP1 SMN1; SMN2 1183/4885EPHX1 1462/4885EPHX2 2733/4885
US-12435035-B2 Nanomaterials NPC1, NPC1L1, FABP1 SMN1; SMN2 1417/4885EPHX1 1514/4885EPHX2 2035/4885
US-20230348361-A1 IONIZABLE LIPID COMPOUNDS PHOSPHO1, SLC10A1, SLCO4C1 SMN1; SMN2 824/4885EPHX1 3592/4885EPHX2 4049/4885
US-20230346702-A1 LIPID NANOPARTICLES ABCB4, NPC1L1, CHMP4B SMN1; SMN2 2092/4885EPHX1 1997/4885EPHX2 2624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.