Sugi Predict

Sugi Predict / Compounds / SCHEMBL1763063

SCHEMBL1763063

SCHEMBL1763063

Cn1nc(C(F)F)c(C(N)=O)c1-c1ccccc1-c1cc(F)c(F)c(F)c1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MGLL Q99685 12/20 0.38
▸ POLB P06746 1/20 0.38
▸ DHODH Q02127 1/20 0.35
▸ CSNK1E P49674 2/20 0.34
▸ CSNK1D P48730 1/20 0.34
▸ TGFBR1 P36897 2/20 0.33
▸ ACVR1 Q04771 2/20 0.33
▸ KCNH2 Q12809 1/20 0.33
▸ ALOX5AP P20292 1/20 0.33
▸ FEN1 P39748 1/20 0.33
▸ CHRM3 P20309 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1762883 0.90 POLB (0.38) MGLLPOLBDHODHCSNK1ECSNK1D
SCHEMBL3325668 0.86 POLB (0.38) POLBCHRM3
SCHEMBL1762881 0.86 CSNK1D (0.41) POLBDHODHCSNK1ECSNK1D
SCHEMBL1763152 0.85 CSNK1E (0.43) POLBCSNK1ECSNK1D
SCHEMBL1762911 0.85 POLB (0.36) MGLLPOLBDHODHCSNK1ECSNK1D
SCHEMBL18691186 0.84 POLB (0.35) MGLLPOLBDHODHCSNK1ECSNK1D
SCHEMBL1763226 0.83 CSNK1E (0.41) MGLLPOLBDHODHCSNK1ECSNK1D
SCHEMBL3329484 0.83 CSNK1D (0.41) POLBDHODHCSNK1ECSNK1DTGFBR1
SCHEMBL1762833 0.82 PTGER4 (0.39) POLBCHRM3
SCHEMBL18691185 0.81 POLB (0.40) MGLLPOLBDHODHCSNK1ECHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010092028-A2 PESTICIDAL MIXTURES BASF SE (DE) 2010-08-19 — — WO claimed
CN-103333113-B The preparation and application study of fluxapyroxad like derivatives 南开大学 2018-09-28 — — CN disclosed
WO-2016030108-A1 USE OF CHLORFENAPYR AND TEFLUBENZURON ON GENETICALLY MODIFIED PLANTS BASF Agro B.V. (NL) 2016-03-03 — — WO disclosed
EP-2941127-A1 CYCLOCLAVINE AND DERIVATIVES THEREOF FOR CONTROLLING INVERTEBRATE PESTS BASF SE (DE) 2015-11-11 — — EP disclosed
WO-2014096238-A1 CYCLOCLAVINE AND DERIVATIVES THEREOF FOR CONTROLLING INVERTEBRATE PESTS BASF SE (DE) 2014-06-26 — — WO disclosed
WO-2014033244-A2 SUBSTITUTED MESOIONIC IMINE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE (DE) 2014-03-06 — — WO disclosed
EP-2579719-A1 METHOD FOR CULTIVATING SUGAR CANE BASF SE (DE) 2013-04-17 — — EP disclosed
US-8263327-B2 Enzymatic method for the production of microcapsules BASF SE (DE) 2012-09-11 — — US disclosed
EP-2443098-A1 ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES BASF SE (DE) 2012-04-25 — — EP disclosed
US-20110124590-A1 Oil-in-Water Emulsion Comprising Solvent, Water, Surfactant and Pesticide BASF SE (DE) 2011-05-26 — — US disclosed
WO-2010146112-A1 ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES BASF SE (DE) 2010-12-23 — — WO disclosed
US-20100120617-A1 Enzymatic Method for the Production of Microcapsules BASF SE 2010-05-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100120617-A1 Enzymatic Method for the Production of Microcapsules MGAM, ACHE, BCHE MGLL 21/4885POLB 565/4885DHODH 371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.