Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.43 |
| ▸ | UCHL1 | P09936 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632437 | 0.87 | USP30 (0.48) | USP30UCHL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL17632002 | 0.75 | CDK9 (0.41) | SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL17631866 | 0.75 | CDK9 (0.41) | SMN1; SMN2CYP1A2NPC1RAB9AALDH1A1 | |
| SCHEMBL17631550 | 0.74 | ABL1 (0.41) | MEN1KMT2ALMNAMAPT | |
| SCHEMBL17632020 | 0.71 | MAPT (0.46) | USP30SMN1; SMN2CYP1A2NPC1RAB9A | |
| SCHEMBL17632381 | 0.70 | USP30 (0.48) | USP30UCHL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL17631709 | 0.68 | FLT3 (0.43) | SMN1; SMN2NPC1 | |
| SCHEMBL17631874 | 0.67 | USP30 (0.51) | USP30 | |
| SCHEMBL17632023 | 0.66 | USP30 (0.42) | USP30UCHL1CYP1A2ALDH1A1LMNA | |
| SCHEMBL17632146 | 0.66 | USP30 (0.41) | USP30MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |