Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 6/20 | 0.51 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17631936 | 0.81 | USP30 (0.37) | USP30CDK9 | |
| SCHEMBL17632195 | 0.81 | CPB1 (0.49) | USP30 | |
| SCHEMBL17632600 | 0.80 | CDK9 (0.39) | CDK9 | |
| SCHEMBL17632095 | 0.80 | USP30 (0.41) | USP30CDK9DYRK1BF10 | |
| SCHEMBL17631943 | 0.80 | USP30 (0.49) | USP30CDK9F10 | |
| SCHEMBL17631671 | 0.80 | USP30 (0.41) | USP30CDK9DYRK1BF10 | |
| SCHEMBL17632326 | 0.80 | USP30 (0.49) | USP30CDK9F10 | |
| SCHEMBL17632437 | 0.79 | USP30 (0.48) | USP30 | |
| SCHEMBL17632381 | 0.79 | USP30 (0.48) | USP30 | |
| SCHEMBL17632335 | 0.79 | USP30 (0.41) | USP30CDK9F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |