Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 13/20 | 0.48 |
| ▸ | UCHL1 | P09936 | 5/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632070 | 0.87 | USP30 (0.43) | USP30UCHL1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL17632381 | 0.83 | USP30 (0.48) | USP30UCHL1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL17631874 | 0.79 | USP30 (0.51) | USP30 | |
| SCHEMBL17631936 | 0.78 | USP30 (0.37) | USP30CHRNB2CHRNA4 | |
| SCHEMBL17632195 | 0.77 | CPB1 (0.49) | USP30UCHL1RAB9ANPC1 | |
| SCHEMBL17632261 | 0.76 | HPGDS (0.41) | USP30 | |
| SCHEMBL17631671 | 0.75 | USP30 (0.41) | USP30 | |
| SCHEMBL17632326 | 0.75 | USP30 (0.49) | USP30 | |
| SCHEMBL17631943 | 0.75 | USP30 (0.49) | USP30 | |
| SCHEMBL17632095 | 0.75 | USP30 (0.41) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |