Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 8/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632095 | 1.00 | USP30 (0.41) | USP30HDAC1HDAC6GSK3BCDK9 | |
| SCHEMBL17632283 | 0.88 | MKNK1 (0.38) | CDK9DYRK1B | |
| SCHEMBL17631644 | 0.85 | CDK9 (0.40) | USP30GSK3BCDK9 | |
| SCHEMBL17632600 | 0.85 | CDK9 (0.39) | CDK9 | |
| SCHEMBL17632326 | 0.84 | USP30 (0.49) | USP30CDK9F10FAAH | |
| SCHEMBL17631943 | 0.84 | USP30 (0.49) | USP30CDK9F10FAAH | |
| SCHEMBL17632335 | 0.83 | USP30 (0.41) | USP30GSK3BCDK9F10FAAH | |
| SCHEMBL17632111 | 0.82 | UCHL1 (0.35) | USP30CDK9DYRK1B | |
| SCHEMBL17631866 | 0.80 | CDK9 (0.41) | GSK3BCDK9 | |
| SCHEMBL17631915 | 0.80 | CDK9 (0.35) | CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |