SCHEMBL17632535

SCHEMBL17632535

CN1CCCC(n2cnc(N)c2)C1

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTR2B P41595 1/20 0.40
TMEM97 Q5BJF2 1/20 0.40
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HTR6 P50406 6/20 0.34
KDM2B Q8NHM5 1/20 0.33
CPB1 P15086 2/20 0.32
CHRM2 P08172 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32
MAP4K4 O95819 1/20 0.32
CPB2 Q96IY4 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17643793 0.90 KDM2B (0.40) HTR2BTMEM97HTR6KDM2BCPB2
SCHEMBL2600275 0.83 HTR2B (0.35) HTR2BTMEM97ATML3MBTL1HTR6
SCHEMBL2822355 0.80 KDM2B (0.48) KDM2BCPB1
SCHEMBL25195947 0.79 CPB1 (0.43) CPB1MAP4K4CPB2
SCHEMBL24925589 0.79 CPB1 (0.40) CPB1CPB2
SCHEMBL20497273 0.79 CPB2 (0.38) HTR2BTMEM97HTR6KDM2BCPB1
Hydrochloric Acid SCHEMBL23389230 0.78 CPB1 (0.39) CPB1CPB2
SCHEMBL25199851 0.78 CPB1 (0.44) CPB1MAP4K4CPB2
Hydrochloric Acid SCHEMBL20588937 0.78 CPB1 (0.42) CPB1MAP4K4CPB2
Hydrochloric Acid SCHEMBL23389336 0.76 CPB1 (0.43) CPB1CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11993595-B2 Compounds MISSION THERAPEUTICS LIMITED (GB) 2024-05-28 US disclosed
CN-111592534-B New compounds 特殊治疗有限公司 2023-06-30 CN disclosed
US-20230052191-A1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2023-02-16 US disclosed
US-11472798-B2 Compounds MISSION THERAPEUTICS LTD (GB) 2022-10-18 US disclosed
EP-3828179-A1 CYANOPYRROLIDINES AS DUB MODULATORS Mission Therapeutics Limited (GB) 2021-06-02 EP disclosed
US-20200369658-A1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2020-11-26 US disclosed
US-10774078-B2 Compounds MISSION THERAPEUTICS LTD (GB) 2020-09-15 US disclosed
CN-111592534-A Novel compounds 特殊治疗有限公司 2020-08-28 CN disclosed
EP-3197883-B1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2020-03-18 EP disclosed
CN-107001339-B Novel compounds 特殊治疗有限公司 2020-03-17 CN disclosed
US-20190330202-A1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2019-10-31 US disclosed
US-10392380-B2 Compounds MISSION THERAPEUTICS LIMITED (GB) 2019-08-27 US disclosed
US-20180162852-A1 NOVEL COMPOUNDS MISSION THERAPEUTICS LIMITED 2018-06-14 US disclosed
US-9926307-B2 Compounds MISSION THERAPEUTICS LTD (GB) 2018-03-27 US disclosed
US-20170247365-A1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2017-08-31 US disclosed
EP-3197883-A1 NOVEL COMPOUNDS Mission Therapeutics Limited (GB) 2017-08-02 EP disclosed
WO-2016046530-A1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2016-03-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10774078-B2 Compounds UCHL1, UCHL3, UCHL5 HTR2B 4643/4885TMEM97 2185/4885ATM 3908/4885
US-11472798-B2 Compounds UCHL1, UCHL3, UCHL5 HTR2B 4643/4885TMEM97 2185/4885ATM 3908/4885
US-20180162852-A1 NOVEL COMPOUNDS UCHL1, UCHL3, UCHL5 HTR2B 4595/4885TMEM97 1592/4885ATM 3738/4885
US-10392380-B2 Compounds UCHL1, UCHL3, UCHL5 HTR2B 4643/4885TMEM97 2185/4885ATM 3908/4885
US-11993595-B2 Compounds UCHL1, UCHL3, UCHL5 HTR2B 4643/4885TMEM97 2185/4885ATM 3908/4885
US-20200369658-A1 NOVEL COMPOUNDS UCHL1, UCHL3, UCHL5 HTR2B 4595/4885TMEM97 1592/4885ATM 3738/4885
US-20190330202-A1 NOVEL COMPOUNDS UCHL1, UCHL3, UCHL5 HTR2B 4595/4885TMEM97 1592/4885ATM 3738/4885
US-20170247365-A1 NOVEL COMPOUNDS UCHL1, UCHL3, UCHL5 HTR2B 4595/4885TMEM97 1592/4885ATM 3738/4885
US-20230052191-A1 NOVEL COMPOUNDS UCHL1, UCHL3, UCHL5 HTR2B 4595/4885TMEM97 1592/4885ATM 3738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.