Sugi Predict

Sugi Predict / Compounds / SCHEMBL17633441

SCHEMBL17633441

SCHEMBL17633441

CS(=O)(=O)c1nnoc1-c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 13/20 0.41
▸ ALDH1A1 P00352 2/20 0.38
▸ HPGD P15428 2/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ CYP1A2 P05177 1/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ NPC1 O15118 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ PTGS1 P23219 1/20 0.35
▸ NR4A2 P43354 1/20 0.34
▸ CA12 O43570 1/20 0.34
▸ CA1 P00915 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22407255 0.85 NPC1 (0.38) PTGS2ALDH1A1KDM4ELMNAKMT2A
SCHEMBL17633442 0.71 PTGS2 (0.43) PTGS2ALDH1A1HPGDLMNACYP3A4
SCHEMBL10166464 0.71 BRD4 (0.44) PTGS2ALDH1A1HPGDHTTKMT2A
SCHEMBL1175088 0.69 NR4A2 (0.44) PTGS2ALDH1A1HPGDKDM4ELMNA
SCHEMBL186399 0.67 NR4A2 (0.42) PTGS2ALDH1A1HPGDKDM4ELMNA
SCHEMBL22158234 0.67 PTPN1 (0.39) ALDH1A1HPGDKDM4ELMNACYP1A2
SCHEMBL11712592 0.67 NR4A2 (0.42) ALDH1A1HPGDKDM4ELMNAKMT2A
SCHEMBL20138609 0.67 PTPN1 (0.40) ALDH1A1HPGDKDM4EKMT2ASMN1; SMN2
SCHEMBL20033943 0.67 GCGR (0.35) PTGS2HPGDKDM4ESMN1; SMN2NPC1
SCHEMBL9829595 0.65 POLB (0.40) ALDH1A1KDM4ELMNAKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025031923-A1 IMIDAZO[4,5-D]PYRIDAZINE COMPOUNDS AND CONJUGATES THEREOF, THEIR PREPARATION, AND THEIR THERAPEUTIC APPLICATIONS SANOFI (FR) 2025-02-13 — — WO claimed
EP-4412659-A1 IMIDAZO[4,5-C]QUINOLINE-4-AMINE COMPOUNDS AND CONJUGATES THEREOF, THEIR PREPARATION, AND THEIR THERAPEUTIC APPLICATIONS Sanofi (FR) 2024-08-14 — — EP claimed
US-20240254092-A1 BIFUNCTIONAL CHELATORS AND CONJUGATES ACTINIUM PHARMACEUTICALS, INC. (US) 2024-08-01 — — US claimed
CN-118302201-A Imidazo [4,5-c ] quinolin-4-amine compounds and conjugates thereof, their preparation and their therapeutic use 赛诺菲 2024-07-05 — — CN claimed
US-11975081-B2 Bifunctional chelators and conjugates ACTINIUM PHARMACEUTICALS, INC. (US) 2024-05-07 — — US claimed
US-11964948-B2 Bifunctional chelators and conjugates ACTINIUM PHARMACEUTICALS, INC. (US) 2024-04-23 — — US claimed
US-20240082438-A1 BIFUNCTIONAL CHELATORS AND CONJUGATES ACTINIUM PHARMACEUTICALS, INC. (US) 2024-03-14 — — US claimed
US-20240051928-A1 BIFUNCTIONAL CHELATORS AND CONJUGATES ACTINIUM PHARMACEUTICALS, INC. (US) 2024-02-15 — — US claimed
WO-2023057564-A1 IMIDAZO[4,5-c]QUINOLINE-4-AMINE COMPOUNDS AND CONJUGATES THEREOF, THEIR PREPARATION, AND THEIR THERAPEUTIC APPLICATIONS SANOFI (FR) 2023-04-13 — — WO claimed
US-20230114866-A1 VIA CYCLOADDITION BILATERALLY FUNCTIONALIZED ANTIBODIES SYNAFFIX B.V. (NL) 2023-04-13 — — US claimed
EP-4090379-A1 VIA CYCLOADDITION BILATERALLY FUNCTIONALIZED ANTIBODIES Synaffix B.V. (NL) 2022-11-23 — — EP claimed
CN-108778341-B Amanita conjugates 海德堡医药研究有限责任公司 2022-11-01 — — CN claimed
CN-115243727-A Bilaterally functionalized antibodies via cycloaddition 西纳福克斯股份有限公司 2022-10-25 — — CN claimed
WO-2021144314-A1 VIA CYCLOADDITION BILATERALLY FUNCTIONALIZED ANTIBODIES SYNAFFIX B.V. (NL) 2021-07-22 — — WO claimed
EP-3624791-B1 REAGENT FOR SITE-SELECTIVE BIOCONJUGATION OF PROTEINS OR ANTIBODIES UNIV CITY NEW YORK RES FOUND (US) 2026-05-06 — — EP disclosed
WO-2026090139-A1 ANTI-LY6K ANTIBODY-DRUG CONJUGATES AND METHODS OF USE NORMUNITY, INC. (US) 2026-04-30 — — WO disclosed
EP-4698231-A1 CLEAVABLE IMMUNE CELL ENGAGERS Synaffix B.V. (NL) 2026-02-25 — — EP disclosed
US-20170360951-A1 BIOLOGICAL MATERIALS AND USES THEREOF ANTIKOR BIOPHARMA LIMITED (GB) 2017-12-21 — — US disclosed
EP-3197501-A1 BIOLOGICAL MATERIALS AND USES THEREOF Antikor Biopharma Limited (GB) 2017-08-02 — — EP disclosed
WO-2016046574-A1 BIOLOGICAL MATERIALS AND USES THEREOF ANTIKOR BIOPHARMA LIMITED (GB) 2016-03-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230114866-A1 VIA CYCLOADDITION BILATERALLY FUNCTIONALIZED ANTIBODIES FUT5, FUCA1, FUT6 PTGS2 3969/4885ALDH1A1 928/4885HPGD 3882/4885
US-20240254092-A1 BIFUNCTIONAL CHELATORS AND CONJUGATES FOLH1, PAICS, TAP2 PTGS2 3849/4885ALDH1A1 2220/4885HPGD 2199/4885
US-11964948-B2 Bifunctional chelators and conjugates FOLH1, PAICS, TAP2 PTGS2 3849/4885ALDH1A1 2220/4885HPGD 2199/4885
US-20240051928-A1 BIFUNCTIONAL CHELATORS AND CONJUGATES FOLH1, PAICS, TAP2 PTGS2 3849/4885ALDH1A1 2220/4885HPGD 2199/4885
US-11975081-B2 Bifunctional chelators and conjugates FOLH1, PAICS, TAP2 PTGS2 3849/4885ALDH1A1 2220/4885HPGD 2199/4885
US-20170360951-A1 BIOLOGICAL MATERIALS AND USES THEREOF CD47, LNPEP, TIE1 PTGS2 3679/4885ALDH1A1 2505/4885HPGD 3338/4885
US-20240082438-A1 BIFUNCTIONAL CHELATORS AND CONJUGATES FOLH1, PAICS, TAP2 PTGS2 3849/4885ALDH1A1 2220/4885HPGD 2199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.