SCHEMBL186399

SCHEMBL186399

c1ccc(-c2onnc2-c2ccc(-c3nnoc3-c3ccccc3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 3/20 0.42
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
PTGS2 P35354 3/20 0.38
PTGS1 P23219 2/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
ALOX15 P16050 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
LMNA P02545 3/20 0.38
MAPK1 P28482 2/20 0.38
HTT P42858 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
TP53 P04637 1/20 0.38
MAPK13 O15264 1/20 0.37
MAPK12 P53778 1/20 0.37
MAPK11 Q15759 1/20 0.37
MAPK14 Q16539 1/20 0.37
KDM4E B2RXH2 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1175088 0.98 NR4A2 (0.44) NR4A2MEN1KMT2APTGS2PTGS1
SCHEMBL28691779 0.91 KMT2A (0.50) NR4A2MEN1KMT2ANPC1RAB9A
Diphenylether SCHEMBL8651099 0.87 LTA4H (0.43) NR4A2MEN1KMT2APTGS1LMNA
SCHEMBL558959 0.85 KIF11 (0.42) MEN1KMT2ANPC1RAB9ATP53
SCHEMBL2200423 0.82 GPR55 (0.42) NR4A2MEN1KMT2APTGS2PTGS1
SCHEMBL2200421 0.82 GPR55 (0.42) NR4A2NPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL11673687 0.81 KMT2A (0.39) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL29872659 0.77 L3MBTL1 (0.49) MEN1KMT2ANPC1RAB9AALOX15
SCHEMBL9176881 0.77 ALDH1A1 (0.48) NR4A2MEN1KMT2ANPC1RAB9A
SCHEMBL11674055 0.76 KIF11 (0.42) KMT2ANPC1RAB9ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11968893-B2 Electroluminescent device UDC IRELAND LIMITED (IE) 2024-04-23 US disclosed
US-20220216422-A1 Electroluminescent Device UDC IRELAND LTD (IE) 2022-07-07 US disclosed
US-11345686-B2 Aromatic amine derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2022-05-31 US disclosed
EP-2315502-B1 Electroluminescent device UDC IRELAND LTD (IE) 2020-10-14 EP disclosed
US-10454038-B2 Delayed-fluorescence material and organic electroluminescence element using same KYULUX, INC. (JP) 2019-10-22 US disclosed
US-20190237675-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-08-01 US disclosed
US-20190177306-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-06-13 US disclosed
US-10312452-B2 Aromatic amine derivative and organic electroluminescence device utilizing the same IDEMITSU KOSAN CO., LTD. (JP) 2019-06-04 US disclosed
US-10246441-B2 Aromatic amine derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2019-04-02 US disclosed
EP-2733762-B1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND COMPOUND USED THEREIN KYULUX INC (JP) 2018-11-28 EP disclosed
US-6251531-B1 LIGHT EMITTING LAYER BETWEEN ANODE AND CATHODE TOYO INK MANUFACTURING CO., LTD. (JP) 2001-06-26 US disclosed
US-6245449-B1 LIGHT EMITTER LAYERS OR ORGANIC COMPOUNDS, THIN LAYERS AND ELECTRODES, ANODES AND CATHODES TOYO INK MANUFACTURING CO., LTD. (JP) 2001-06-12 US disclosed
EP-1061112-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN COMPANY LIMITED (JP) 2000-12-20 EP disclosed
US-6150042-A ELECTROLUMINESCENCE DEVICE WITH HOLE INJECTING MATERIAL HAVING GOOD DURABILITY BEING A TRIPHENYLENE STRUCTURE OF GIVEN FORMULA HAVING MULTIPLE ETHER, SULFIDE, AND/OR AMINE SUBSTITUTIONS TOYO INK MANUFACTURING CO., LTD. (JP) 2000-11-21 US disclosed
EP-0965629-A1 Compound for organic electroluminescence device and organic electroluminescence device TOYO INK MFG. CO., LTD. (JP) 1999-12-22 EP disclosed
EP-0934992-A1 Light-emitting material for organo-electroluminescence device and organic electroluminescence device TOYO INK MANUFACTURING CO., LTD. (JP) 1999-08-11 EP disclosed
EP-0866110-A1 Light-emitting material for organo-electroluminescence device and organic electroluminescence device TOYO INK MANUFACTURING CO., LTD. (JP) 1998-09-23 EP disclosed
EP-0847228-A2 Material for organoelectroluminescence device and use thereof TOYO INK MANUFACTURING CO., LTD. (JP) 1998-06-10 EP disclosed
EP-0786926-A2 Light-emitting material for organo-electroluminescence device and organo-electroluminescence devive for which the light-emitting material is adapted TOYO INK MANUFACTURING CO., LTD. (JP) 1997-07-30 EP disclosed
EP-0765106-A2 Light-emitting material for organic electroluminescence device, and organic electroluminescence device for which the light-emitting material is adapted TOYO INK MANUFACTURING CO., LTD. (JP) 1997-03-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10312452-B2 Aromatic amine derivative and organic electroluminescence device utilizing the same TYR, OCIAD2, MAOA NR4A2 2456/4885MEN1 2216/4885KMT2A 211/4885
US-10246441-B2 Aromatic amine derivative, and organic electroluminescent element MAOB, MAOA, NAT1 NR4A2 1284/4885MEN1 1990/4885KMT2A 564/4885
US-20190177306-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT TYR, LEF1, EFNA1 NR4A2 1938/4885MEN1 2298/4885KMT2A 563/4885
US-20220216422-A1 Electroluminescent Device PNPO, ODC1, AXL NR4A2 904/4885MEN1 1878/4885KMT2A 2012/4885
US-10454038-B2 Delayed-fluorescence material and organic electroluminescence element using same HNRNPF, RABL6, SRSF6 NR4A2 1256/4885MEN1 2086/4885KMT2A 1861/4885
US-11345686-B2 Aromatic amine derivative, and organic electroluminescent element TYR, LEF1, EFNA1 NR4A2 1938/4885MEN1 2298/4885KMT2A 563/4885
US-11968893-B2 Electroluminescent device PNPO, ODC1, AXL NR4A2 904/4885MEN1 1878/4885KMT2A 2012/4885
US-20190237675-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME TYR, NLRP1, NLRP3 NR4A2 2050/4885MEN1 2466/4885KMT2A 460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.