Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1562023 | 0.85 | ALDH1A1 (0.50) | SOAT1CYP4F2CYP4A11ALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL5446995 | 0.82 | ALDH1A1 (0.48) | SOAT1CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL27825812 | 0.82 | HCAR2 (0.36) | SOAT1ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL18799245 | 0.82 | CYP4F2 (0.40) | SOAT1CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL3844760 | 0.82 | ALDH1A1 (0.48) | SOAT1CYP4F2CYP4A11ALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL3845860 | 0.80 | ALOX15 (0.39) | SOAT1CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL22773965 | 0.80 | TDP1 (0.32) | SOAT1ALDH1A1 | |
| Butane SCHEMBL11358505 | 0.80 | ALDH1A1 (0.46) | SOAT1CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL13917982 | 0.79 | ALDH1A1 (0.50) | CYP4F2CYP4A11ALDH1A1PKMLMNA | |
| SCHEMBL46634 | 0.79 | CYP4F2 (0.38) | CYP4F2CYP4A11ALDH1A1PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106047273-B | Novel stabilizer and application thereof in dealcoholized RTV-1 silicone rubber composition | 浙江新安化工集团股份有限公司 | 2020-05-12 | — | — | CN | disclosed |
| US-9974777-B2 | Tetrahydrocarboline derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2018-05-22 | — | — | US | disclosed |
| US-20170189386-A1 | TETRAHYDROCARBOLINE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2017-07-06 | — | — | US | disclosed |
| US-9673048-B2 | Method of producing thin film transistor, thin film transistor, display device, image sensor, and X-ray sensor | FUJIFILM CORPORATION (JP) | 2017-06-06 | — | — | US | disclosed |
| US-9636330-B2 | Tetrahydrocarboline derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2017-05-02 | — | — | US | disclosed |
| US-9543143-B2 | Method for producing amorphous oxide thin film and thin film transistor | FUJIFILM CORPORATION (JP) | 2017-01-10 | — | — | US | disclosed |
| US-20150231118-A1 | TETRAHYDROCARBOLINE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2015-08-20 | — | — | US | disclosed |
| US-20150175587-A1 | SYNTHESIS OF EPOTHILONES, INTERMEDIATES THERETO AND ANALOGUES THEREOF | SLOAN KETTERING INST CANCER (US) | 2015-06-25 | — | — | US | disclosed |
| US-20150103977-A1 | METHOD OF PRODUCING THIN FILM TRANSISTOR, THIN FILM TRANSISTOR, DISPLAY DEVICE, IMAGE SENSOR, AND X-RAY SENSOR | SAMSUNG DISPLAY CO., LTD. (KR) | 2015-04-16 | — | — | US | disclosed |
| US-9006246-B2 | Tetrahydrocarboline derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2015-04-14 | — | — | US | disclosed |
| WO-2004018478-A2 | SYNTHESIS OF EPOTHILONES, INTERMEDIATES THERETO, ANALOGUES AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2004-03-04 | — | — | WO | disclosed |
| US-20030232136-A1 | Layer formation method, and substrate with a layer formed by the method | KONICA CORPORATION (JP) | 2003-12-18 | — | — | US | disclosed |
| EP-1371752-A2 | Layer formation method, and substrate with a layer formed by the method | KONICA CORPORATION (JP) | 2003-12-17 | — | — | EP | disclosed |
| WO-2003092586-A2 | TETRAHYDROPYRANYL CYCLOPENTYL TETRAHYDROPYRIDOPYRIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2003-11-13 | — | — | WO | disclosed |
| WO-2003072102-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-09-04 | — | — | WO | disclosed |
| CN-1201790-A | Herbicide | MITSUBISHI CHEM CORP (JP) | 1998-12-16 | — | — | CN | disclosed |
| US-5726128-A | Benzyloxypyrimidine derivative, processes for producing the same and herbicidal composition | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-03-10 | — | — | US | disclosed |
| US-5723412-A | HERBICIDES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0707001-A1 | Benzyloxypyrimidine derivative, processes for producing the same and herbicidal composition | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-04-17 | — | — | EP | disclosed |
| EP-0694538-A2 | 2-benzyloxy-4-phenoxypyrimidine derivative, processes for producing the derivative and herbicidal composition containing the derivative | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-01-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150175587-A1 | SYNTHESIS OF EPOTHILONES, INTERMEDIATES THERETO AND ANALOGUES THEREOF | DHPS, THPO, CYP11B1 | SOAT1 275/4885CYP4F2 120/4885CYP4A11 12/4885 |
| US-20170189386-A1 | TETRAHYDROCARBOLINE DERIVATIVE | ENPP2, ENPP1, ACER2 | SOAT1 1402/4885CYP4F2 698/4885CYP4A11 798/4885 |
| US-20150231118-A1 | TETRAHYDROCARBOLINE DERIVATIVE | ENPP2, ENPP1, ACER2 | SOAT1 1432/4885CYP4F2 754/4885CYP4A11 906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.