Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11809119 | 0.81 | ALDH1A1 (0.35) | LMNA | |
| SCHEMBL304553 | 0.78 | — | — | |
| SCHEMBL3072776 | 0.76 | LMNA (0.38) | CRBNLMNA | |
| Methane SCHEMBL3764799 | 0.76 | — | — | |
| SCHEMBL30230076 | 0.76 | — | — | |
| SCHEMBL11470161 | 0.76 | — | — | |
| SCHEMBL28874017 | 0.76 | — | — | |
| SCHEMBL30363497 | 0.76 | — | — | |
| SCHEMBL20587385 | 0.74 | — | — | |
| Nitric Acid SCHEMBL25282444 | 0.73 | CA5A (0.50) | CRBNLMNACYP1A2TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207448-B | Antimicrobial compounds, methods of making the same, and articles comprising the same | 医学科技研究公司 | 2020-12-29 | — | — | CN | claimed |
| US-10189798-B2 | Antimicrobial compounds, methods of making the same and articles comprising them | MEDICAL TECHNOLOGY RESEARCH INC (US) | 2019-01-29 | — | — | US | claimed |
| US-20180134672-A1 | ANTIMICROBIAL COMPOUNDS, METHODS OF MAKING THE SAME AND ARTICLES COMPRISING THEM | MEDICAL TECHNOLOGY RESEARCH INC | 2018-05-17 | — | — | US | claimed |
| EP-3201182-A2 | ANTIMICROBIAL COMPOUNDS, METHODS OF MAKING THE SAME AND ARTICLES COMPRISING THEM | Medical Technology Research Inc. (US) | 2017-08-09 | — | — | EP | claimed |
| WO-2016054284-A2 | ANTIMICROBIAL COMPOUNDS, METHODS OF MAKING THE SAME AND ARTICLES COMPRISING THEM | MEDICAL TECHNOLOGY RESEARCH INC (US) | 2016-04-07 | — | — | WO | claimed |
| CN-109641842-B | 1-phenyl-3-carbamoylurea compounds and uses thereof | 住友化学株式会社 | 2021-12-07 | — | — | CN | disclosed |
| CN-107207448-B | Antimicrobial compounds, methods of making the same, and articles comprising the same | 医学科技研究公司 | 2020-12-29 | — | — | CN | disclosed |
| US-10844019-B2 | 1-phenyl-3-carbamoyl urea compound, and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-11-24 | — | — | US | disclosed |
| CN-107573263-B | Synthetic method of omega-substituted biuret compound | 大连理工大学 | 2020-04-07 | — | — | CN | disclosed |
| US-20190202787-A1 | 1-PHENYL-3-CARBAMOYL UREA COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2019-07-04 | — | — | US | disclosed |
| CN-109641842-A | 1- phenyl -3- carbamoyl carbamide compound and application thereof | 住友化学株式会社 | 2019-04-16 | — | — | CN | disclosed |
| US-10189798-B2 | Antimicrobial compounds, methods of making the same and articles comprising them | MEDICAL TECHNOLOGY RESEARCH INC (US) | 2019-01-29 | — | — | US | disclosed |
| US-20180134672-A1 | ANTIMICROBIAL COMPOUNDS, METHODS OF MAKING THE SAME AND ARTICLES COMPRISING THEM | MEDICAL TECHNOLOGY RESEARCH INC | 2018-05-17 | — | — | US | disclosed |
| CN-107573263-A | A kind of synthetic method of ω substitutions biuret class compound | 大连理工大学 | 2018-01-12 | — | — | CN | disclosed |
| CN-107207448-A | Antimicrobial compounds, methods of making the same, and articles comprising the same | 医学科技研究公司 | 2017-09-26 | — | — | CN | disclosed |
| EP-3201182-A2 | ANTIMICROBIAL COMPOUNDS, METHODS OF MAKING THE SAME AND ARTICLES COMPRISING THEM | Medical Technology Research Inc. (US) | 2017-08-09 | — | — | EP | disclosed |
| WO-2016054284-A2 | ANTIMICROBIAL COMPOUNDS, METHODS OF MAKING THE SAME AND ARTICLES COMPRISING THEM | MEDICAL TECHNOLOGY RESEARCH INC (US) | 2016-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10189798-B2 | Antimicrobial compounds, methods of making the same and articles comprising them | GSDMD, TIAL1, AAAS | CRBN 1309/4885LMNA 4714/4885CYP1A2 2158/4885 |
| US-20180134672-A1 | ANTIMICROBIAL COMPOUNDS, METHODS OF MAKING THE SAME AND ARTICLES COMPRISING THEM | GSDMD, TIAL1, AAAS | CRBN 1309/4885LMNA 4714/4885CYP1A2 2158/4885 |
| US-10844019-B2 | 1-phenyl-3-carbamoyl urea compound, and use thereof | CPS1, SLC14A1, UBA1 | CRBN 2179/4885LMNA 3310/4885CYP1A2 2538/4885 |
| US-20190202787-A1 | 1-PHENYL-3-CARBAMOYL UREA COMPOUND, AND USE THEREOF | CPS1, SLC14A1, UBA1 | CRBN 2179/4885LMNA 3310/4885CYP1A2 2538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.