Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 2/20 | 0.46 |
| ▸ | TPMT | P51580 | 2/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL205882 | 0.88 | TPMT (0.56) | KDM4EGAAL3MBTL1TSHRTPMT | |
| SCHEMBL68014 | 0.88 | ALDH1A1 (0.57) | ALDH1A1KDM4EGAAL3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL4352471 | 0.86 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAAL3MBTL1TSHR | |
| SCHEMBL14950582 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KDM4EGAAL3MBTL1TSHR | |
| SCHEMBL14950602 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KDM4EGAAL3MBTL1TSHR | |
| SCHEMBL14947555 | 0.81 | HSD17B1 (0.51) | ALDH1A1KDM4EGAAL3MBTL1TSHR | |
| SCHEMBL17656285 | 0.81 | HCRTR1 (0.48) | ALDH1A1KDM4EGAAALOX15HSD17B10 | |
| SCHEMBL590030 | 0.80 | TPMT (0.52) | ALDH1A1KDM4EGAAL3MBTL1TSHR | |
| SCHEMBL29602624 | 0.80 | TPMT (0.52) | ALDH1A1KDM4EGAAL3MBTL1TSHR | |
| SCHEMBL498268 | 0.80 | TSHR (0.52) | ALDH1A1KDM4EGAAL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3002281-B1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2017-09-13 | — | — | EP | disclosed |
| EP-3002281-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2016-04-06 | — | — | EP | disclosed |