SCHEMBL1765946

SCHEMBL1765946

Nc1nc(=O)[nH]cc1S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5143009 0.76
SCHEMBL3292019 0.76
SCHEMBL1231792 0.73 ATAD2 (0.37)
SCHEMBL65897 0.73
Flucytosine SCHEMBL8160959 0.73 ALDH1A1 (0.37)
Flucytosine SCHEMBL24063 0.73
SCHEMBL22008 0.73
SCHEMBL30609151 0.73
SCHEMBL29061386 0.73
SCHEMBL65486 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107823644-A A kind of application of NO compound donators in the invasion and attack and transfer ability medicine that suppress the tumour cell rich in thiol molecule are prepared 福州大学 2018-03-23 CN claimed
EP-2013344-B1 ANTISENSE AGENTS COMBINING STRONGLY BOUND BASE - MODIFIED OLIGONUCLEOTIDE AND ARTIFICIAL NUCLEASE BALTIC TECHNOLOGY DEV LTD (EE) 2012-08-29 EP claimed
US-20120171279-A1 STRONGLY BOUND BASE-MODIFIED OLIGONUCLEOTIDES Baltic Technology Development Ltd. (EE) 2012-07-05 US claimed
US-20110171287-A1 Use of Oligonucleotides with Modified Bases as Antiviral Agents BALTIC TECHNOLOGY DEVELPMENT, LTD. (EE) 2011-07-14 US claimed
US-20110152346-A1 Use of Oligonucleotides with Modified Bases in Hybridization of Nucleic Acids Baltic Technology Development Ltd. (EE) 2011-06-23 US claimed
CN-101983241-A Use of oligonucleotides with modified bases in hybridization of nucleic acids BALTIC TECHNOLOGY DEV LTD 2011-03-02 CN claimed
CN-101970662-A Use of oligonucleotides with modified bases as antiviral agents BALTIC TECHNOLOGY DEV LTD 2011-02-09 CN claimed
US-7786292-B2 compounds having a chelating moiety and an oligonucleotide sequence which includes one or more modified nucleobases such as hydroxynucleobases; inhibiting translation of a nucleic acid in an organism BALTIC TECHNOLOGY DEVELOPMENT, LTD. (EE) 2010-08-31 US claimed
EP-2217705-A2 USE OF OLIGONUCLEOTIDES WITH MODIFIED BASES IN HYBRIDIZATION OF NUCLEIC ACIDS Baltic Technology Development, Ltd. (EE) 2010-08-18 EP claimed
EP-2212420-A2 USE OF OLIGONUCLEOTIDES WITH MODIFIED BASES AS ANTIVIRAL AGENTS Baltic Technology Development, Ltd. (EE) 2010-08-04 EP claimed
WO-2009144365-A1 USE OF OLIGONUCLEOTIDES WITH MODIFIED BASES AS ANTIVIRAL AGENTS BALTIC TECHNOLOGY DEVELOPMENT, LTD. (EE) 2009-12-03 WO claimed
CN-101437943-A Antisense agents combining strongly bound base - modified oligonucleotide and artificial nuclease BALTIC TECHNOLOGY DEV LTD (EE) 2009-05-20 CN claimed
WO-2009060122-A2 USE OF OLIGONUCLEOTIDES WITH MODIFIED BASES AS ANTIVIRAL AGENTS BALTIC TECHNOLOGY DEVELOPMENT, LTD. (EE) 2009-05-14 WO claimed
WO-2009060124-A2 USE OF OLIGONUCLEOTIDES WITH MODIFIED BASES IN HYBRIDIZATION OF NUCLEIC ACIDS BALTIC TECHNOLOGY DEVELOPMENT, LTD. (EE) 2009-05-14 WO claimed
EP-2013344-A2 ANTISENSE AGENTS COMBINING STRONGLY BOUND BASE - MODIFIED OLIGONUCLEOTIDE AND ARTIFICIAL NUCLEASE Baltic Technology Development, Ltd. (EE) 2009-01-14 EP claimed
WO-2007125173-A2 ANTISENSE AGENTS COMBINING STRONGLY BOUND BASE - MODIFIED OLIGONUCLEOTIDE AND ARTIFICIAL NUCLEASE BALTIC TECHNOLOGY DEVELOPMENT, LTD. (EE) 2007-11-08 WO claimed
US-20070259830-A1 Antisense Agents Combining Strongly Bound Base-Modified Oligonucleotide and Artificial Nuclease BALTIC TECHNOLOGY DEVELOPMENT (EE) 2007-11-08 US claimed
CN-119912512-A Comprising a trithiophosphate oligonucleotides with internucleoside linkages 罗氏创新中心哥本哈根有限公司 2025-05-02 CN disclosed
EP-0288163-A2 Oligodeoxynucleotides as inhibitors of the replication of retroviruses and the expression of oncogenes THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) 1988-10-26 EP disclosed
WO-1988007544-A1 INHIBITORS FOR REPLICATION OF RETROVIRUSES AND FOR THE EXPRESSION OF ONCOGENE PRODUCTS UNITED STATES OF AMERICA, REPRESENTED BY THE UNITE (US) 1988-10-06 WO disclosed