Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ME2 | P23368 | 1/20 | 0.42 |
| ▸ | ME1 | P48163 | 1/20 | 0.42 |
| ▸ | ME3 | Q16798 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17659681 | 0.81 | GAA (0.41) | GAAALDH1A1LMNAMAPTALOX15 | |
| SCHEMBL29236372 | 0.81 | GAA (0.41) | GAAALDH1A1LMNAMAPTALOX15 | |
| SCHEMBL17659026 | 0.80 | GAA (0.48) | GAAALDH1A1LMNAMAPTALOX15 | |
| SCHEMBL17659014 | 0.74 | ALDH1A1 (0.50) | GAAALDH1A1LMNAGFERMAPT | |
| SCHEMBL17659703 | 0.74 | MEN1 (0.40) | GAAALDH1A1LMNAGFERMAPT | |
| SCHEMBL17659670 | 0.73 | LMNA (0.47) | GAAALDH1A1LMNAGFERMAPT | |
| SCHEMBL17659123 | 0.73 | DRD2 (0.51) | GAAALDH1A1MAPT | |
| SCHEMBL17659041 | 0.73 | ALOX15 (0.58) | GAAALDH1A1LMNAMAPTALOX15 | |
| SCHEMBL17658986 | 0.73 | CYP2D6 (0.45) | ALDH1A1 | |
| SCHEMBL3926124 | 0.72 | KMT2A (0.42) | GAAALDH1A1LMNAMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016051799-A1 | 2-AMINOHYDROQUINONE DERIVATIVE AND TAU AGGREGATION INHIBITOR | 学校法人同志社 | 2016-04-07 | — | — | WO | disclosed |