Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 4/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | USP9X | Q93008 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OGG1 | O15527 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5744363 | 0.87 | S1PR3 (0.51) | S1PR3S1PR2USP9XKEAP1NFE2L2 | |
| SCHEMBL7397371 | 0.84 | S1PR3 (0.47) | S1PR3S1PR2SYKTRPM8KEAP1 | |
| SCHEMBL23716154 | 0.84 | ROCK2 (0.48) | SYKTRPM8KEAP1NFE2L2OGG1 | |
| SCHEMBL13710935 | 0.84 | ROCK2 (0.48) | SYKTRPM8KEAP1NFE2L2OGG1 | |
| SCHEMBL13707887 | 0.81 | ALDH1A1 (0.49) | S1PR3S1PR2SYKTRPM8SMN1; SMN2 | |
| SCHEMBL17664004 | 0.80 | S1PR3 (0.54) | S1PR3S1PR2SYKTRPM8SMN1; SMN2 | |
| SCHEMBL19658438 | 0.80 | LMNA (0.46) | LMNA | |
| SCHEMBL19658733 | 0.80 | LMNA (0.46) | LMNA | |
| SCHEMBL12880512 | 0.80 | LMNA (0.46) | LMNA | |
| SCHEMBL17664466 | 0.79 | S1PR3 (0.51) | S1PR3S1PR2KEAP1NFE2L2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016053855-A1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-04-07 | — | — | WO | disclosed |