Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18908785 | 0.84 | LMNA (0.39) | PTGDR2KDRCYP1A2KDM4ELMNA | |
| SCHEMBL19501576 | 0.81 | PTGDR2 (0.40) | PTGDR2TSHRCYP1A2DDR1ALOX5AP | |
| SCHEMBL17664492 | 0.79 | FEN1 (0.46) | SCN9AKDRMAPK14TNNI3KALOX5AP | |
| SCHEMBL17664477 | 0.77 | SCN9A (0.41) | SCN9APTGDR2KDRMAPK14TNNI3K | |
| SCHEMBL17664494 | 0.76 | CRHR1 (0.39) | SCN9APTGDR2CYP1A2DDR1CRHR1 | |
| SCHEMBL18843178 | 0.75 | DDR1 (0.38) | PTGDR2CYP1A2MAPK1DDR1CRHR1 | |
| SCHEMBL22809140 | 0.74 | GABRG2 (0.46) | CYP2C19CYP1A2KDM4ELMNAMAPK1 | |
| Methane SCHEMBL23369618 | 0.74 | DDR1 (0.37) | PTGDR2CYP1A2MAPK1DDR1CRHR1 | |
| SCHEMBL18785056 | 0.73 | ALOX5AP (0.39) | PTGDR2CYP1A2KDM4EDDR1ALOX5AP | |
| SCHEMBL28074599 | 0.73 | TSHR (0.43) | KDRMAPK14TNNI3KTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3202762-B1 | PYRIMIDINONE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2019-06-19 | — | — | EP | disclosed |
| US-9802930-B1 | Pyrimidinone compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-31 | — | — | US | disclosed |
| US-20170305896-A1 | PYRIMIDINONE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-26 | — | — | US | disclosed |
| EP-3202762-A1 | PYRIMIDINONE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2017-08-09 | — | — | EP | disclosed |
| WO-2017090654-A1 | PEST CONTROL COMPOSITION AND USE THEREOF | 住友化学株式会社 | 2017-06-01 | — | — | WO | disclosed |
| WO-2016052247-A1 | PYRIMIDINONE COMPOUND | 住友化学株式会社 | 2016-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305896-A1 | PYRIMIDINONE COMPOUND | C5, C3AR1, CCR3 | SCN9A 2811/4885PTGDR2 1449/4885KDR 1551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.