Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28208378 | 0.84 | ELANE (0.36) | FBP1ELANERAB9ACYP17A1PCSK9 | |
| SCHEMBL28434035 | 0.83 | RAB9A (0.33) | ELANERAB9APCSK9NPC1KMT2A | |
| SCHEMBL126581 | 0.82 | ELANE (0.35) | FBP1ELANERAB9ACYP17A1PCSK9 | |
| SCHEMBL805980 | 0.82 | NOS1 (0.40) | FBP1ELANERAB9ACYP17A1PCSK9 | |
| SCHEMBL19291519 | 0.79 | ELANE (0.33) | FBP1ELANERAB9ACYP17A1PCSK9 | |
| SCHEMBL19532466 | 0.79 | ELANE (0.33) | FBP1ELANERAB9ACYP17A1PCSK9 | |
| SCHEMBL14135 | 0.77 | RAB9A (0.32) | ELANERAB9APCSK9NOS1L3MBTL1 | |
| SCHEMBL13221 | 0.77 | RAB9A (0.32) | ELANERAB9APCSK9NOS1L3MBTL1 | |
| SCHEMBL13518677 | 0.77 | RAB9A (0.32) | ELANERAB9APCSK9PLAUNOS1 | |
| SCHEMBL13518680 | 0.77 | RAB9A (0.32) | ELANERAB9APCSK9PLAUNOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016054261-A1 | SPHINGOSINE KINASE INHIBITORS | LYNCH KEVIN (US) | 2016-04-07 | — | — | WO | disclosed |