SCHEMBL14135

SCHEMBL14135

CC(C)(C)OC(=O)/N=C(/NC(=O)OC(C)(C)C)n1cccn1

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.32
ELANE P08246 1/20 0.32
PCSK9 Q8NBP7 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
NOS1 P29475 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13221 1.00 RAB9A (0.32) RAB9AELANEPCSK9L3MBTL1NOS1
SCHEMBL8121 1.00 RAB9A (0.32) RAB9AELANEPCSK9L3MBTL1NOS1
SCHEMBL2343819 0.89 ELANE (0.35) ELANENOS1
SCHEMBL17560519 0.89 ELANE (0.35) ELANENOS1
SCHEMBL17654422 0.89 RAB9A (0.32) RAB9AELANEPCSK9L3MBTL1NOS1
SCHEMBL2127300 0.89 ELANE (0.35) ELANENOS1
SCHEMBL13518677 0.89 RAB9A (0.32) RAB9AELANEPCSK9L3MBTL1NOS1
SCHEMBL13518680 0.89 RAB9A (0.32) RAB9AELANEPCSK9L3MBTL1NOS1
SCHEMBL25504021 0.89 ELANE (0.32) ELANENOS1
SCHEMBL24177802 0.89 PCSK9 (0.33) ELANEPCSK9NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 811 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10155009-B2 Polyion complex of poly(L-arginine) segment-containing block copolymer and polyanionic polymer General Incorporated Association Tsukuba Global Innovation Promotion Agency (JP) 2018-12-18 US claimed
US-20180085395-A1 POLYION COMPLEX OF POLY(L-ARGININE) SEGMENT-CONTAINING BLOCK COPOLYMER AND POLYANIONIC POLYMER General Incorporated Association Tsukuba Global Innovation Promotion Agency (JP) 2018-03-29 US claimed
EP-3284474-A1 POLYION COMPLEX OF POLY(L-ARGININE) SEGMENT-CONTAINING BLOCK COPOLYMER AND POLYANIONIC POLYMER General Incorporated Association Tsukuba Global Innovation Promotion Agency (JP) 2018-02-21 EP claimed
EP-4720058-A2 BIFUNCTIONAL DEGRADERS AND USES THEREOF Casma Therapeutics, Inc. (US) 2026-04-08 EP disclosed
US-12590083-B2 Inhibitors of spinster homolog 2 (SPNS2) for use in therapy UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2026-03-31 US disclosed
US-12544359-B2 1-aminosulfonyl-2-carboxypyrrole derivatives as metallo-beta-lactamase inhibitors Infex Therapeutics Limited (GB) 2026-02-10 US disclosed
US-20260035357-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCE INC (US) 2026-02-05 US disclosed
US-12540161-B2 Linkers BICYCLETX LIMITED (GB) 2026-02-03 US disclosed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
US-20260015337-A1 COMPOUNDS FOR TREATMENT A CORONAVIRUS INFECTION TRAWSFYNYDD THERAPEUTICS INC (US) 2026-01-15 US disclosed
EP-4321524-B1 LIPID AND COMPOSITION SOGO PHARM (JP) 2025-12-10 EP disclosed
US-5856309-A TREATING OSTEOPOROSIS, INFLAMMATION OR A DISEASE WHICH IS DUE TO A THROMBOEMBOLIC EVENT BOEHRINGER MANNHEIM GMBH (DE) 1999-01-05 US disclosed
EP-0833825-A4 6-CARBOXAMIDO DIHYDROPYRAN DERIVATIVES BIOTA SCIENT MANAGEMENT (AU) 1998-10-07 EP disclosed
US-5763483-A NEURAMINIDASE INHIBITOR TREATING INFLUENZA VIRUS INFECTION; OSELTAMIVIR OR THE FREE ACID THEREOF; FDA ORANGE BOOK LISTED PATENT FOR OSELTAMIVIR PHOSPHATE GILEAD SCIENCES, INC. (US) 1998-06-09 US disclosed
EP-0833825-A1 6-CARBOXAMIDO DIHYDROPYRAN DERIVATIVES BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) 1998-04-08 EP disclosed
WO-1998007420-A1 NEUROPEPTIDE-Y LIGANDS AGOURON ACQUISITION CORP. (US) 1998-02-26 WO disclosed
EP-0759917-A1 NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES GILEAD SCIENCES, INC. (US) 1997-03-05 EP disclosed
WO-1996026933-A9 NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES 1996-11-28 WO disclosed
WO-1996036628-A1 6-CARBOXAMIDO DIHYDROPYRAN DERIVATIVES BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) 1996-11-21 WO disclosed
WO-1996026933-A1 NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES GILEAD SCIENCES, INC. (US) 1996-09-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12544359-B2 1-aminosulfonyl-2-carboxypyrrole derivatives as metallo-beta-lactamase inhibitors CBR1, CBR3, SRR RAB9A 2160/4885ELANE 3408/4885PCSK9 1278/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 RAB9A 1211/4885ELANE 2120/4885PCSK9 3587/4885
US-20260015337-A1 COMPOUNDS FOR TREATMENT A CORONAVIRUS INFECTION ACE2, ACE, TMPRSS2 RAB9A 1612/4885ELANE 1542/4885PCSK9 133/4885
US-10155009-B2 Polyion complex of poly(L-arginine) segment-containing block copolymer and polyanionic polymer ARG1, NOS2, ARG2 RAB9A 4637/4885ELANE 2025/4885PCSK9 4231/4885
US-20180085395-A1 POLYION COMPLEX OF POLY(L-ARGININE) SEGMENT-CONTAINING BLOCK COPOLYMER AND POLYANIONIC POLYMER ARG1, NOS2, ARG2 RAB9A 4637/4885ELANE 2025/4885PCSK9 4231/4885
US-12590083-B2 Inhibitors of spinster homolog 2 (SPNS2) for use in therapy SPNS2, SLC20A2, S1PR2 RAB9A 1729/4885ELANE 3151/4885PCSK9 216/4885
US-20260035357-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION CCR10, CCR1, CCR3 RAB9A 748/4885ELANE 1336/4885PCSK9 2450/4885
US-12540161-B2 Linkers ADM2, CDA, DCTD RAB9A 3905/4885ELANE 4271/4885PCSK9 3833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.