SCHEMBL13221

SCHEMBL13221

CC(C)(C)OC(=O)/N=C(\NC(=O)OC(C)(C)C)n1cccn1

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.32
ELANE P08246 1/20 0.32
PCSK9 Q8NBP7 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
NOS1 P29475 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14135 1.00 RAB9A (0.32) RAB9AELANEPCSK9L3MBTL1NOS1
SCHEMBL8121 1.00 RAB9A (0.32) RAB9AELANEPCSK9L3MBTL1NOS1
SCHEMBL2343819 0.89 ELANE (0.35) ELANENOS1
SCHEMBL17560519 0.89 ELANE (0.35) ELANENOS1
SCHEMBL17654422 0.89 RAB9A (0.32) RAB9AELANEPCSK9L3MBTL1NOS1
SCHEMBL2127300 0.89 ELANE (0.35) ELANENOS1
SCHEMBL13518677 0.89 RAB9A (0.32) RAB9AELANEPCSK9L3MBTL1NOS1
SCHEMBL13518680 0.89 RAB9A (0.32) RAB9AELANEPCSK9L3MBTL1NOS1
SCHEMBL25504021 0.89 ELANE (0.32) ELANENOS1
SCHEMBL24177802 0.89 PCSK9 (0.33) ELANEPCSK9NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 467 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12516049-B2 Sulfonylurea ring substituted monocyclic β-lactam antibiotics SUZHOU ERYE PHARMACEUTICAL CO., LTD (CN) 2026-01-06 US disclosed
EP-3528813-B1 P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS ABS DEV 1 INC (US) 2025-04-16 EP disclosed
US-20250115561-A1 BIPHENYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS PARION SCIENCES, INC. (US) 2025-04-10 US disclosed
EP-4469441-A1 BIPHENYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS Parion Sciences, Inc. (US) 2024-12-04 EP disclosed
US-20240391925-A1 P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS ASANA BIOSCIENCES, LLC (US) 2024-11-28 US disclosed
US-12077543-B2 P2X3 and/or P2X2/3 compounds and methods ASANA BIOSCIENCES, LLC (US) 2024-09-03 US disclosed
US-20240239790-A1 7-Morpholino-1,6-Naphthyridin-5-yl Derivatives and Pharmaceutical Compositions Thereof Useful as DNA-PK Inhibitor LIFEARC (GB) 2024-07-18 US disclosed
WO-2024123663-A1 ANTIMICROBIAL COMPOUNDS SRI INTERNATIONAL (US) 2024-06-13 WO disclosed
WO-2024092256-A2 PEPTIDE-ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS EISAI R&D MANAGEMENT CO., LTD. (JP) 2024-05-02 WO disclosed
US-20240066135-A1 DRUG CONJUGATES AND USES THEREOF SUPERTRANS MEDICAL LTD (IL) 2024-02-29 US disclosed
WO-2003051797-A2 SMALL-MOLECULE INHIBITORS OF INTERLEUKIN-2 SUNESIS PHARMACEUTICALS, INC. (US) 2003-06-26 WO disclosed
US-20030087950-A1 New alpha-amino acid sulphonyl compounds LES LABORATOIRES SERVIER (FR) 2003-05-08 US disclosed
EP-1245568-A1 Sulfonyl derivatives of amino acids and their use as inhibitors of dipeptidyl-peptidase IV (DPP IV) Les Laboratoires Servier (FR) 2002-10-02 EP disclosed
EP-1187825-A1 THIOPHENE INTEGRIN INHIBITORS Shire Biochem Inc. (CA) 2002-03-20 EP disclosed
US-6274620-B1 2-BENZENESULFONYLAMINO-3-((5-BROMO-THIOPHENE-2-CARBONYL)-AMINO )PROPIONIC ACID-TERT-BUTYL ESTERS AS ANGIOGENESIS INHIBITORS; ANTICARCINOGENIC AGENTS; OSTEOPOROSIS, RESTENOSIS, AND OCULAR NEOVASCULARIZATION BIOCHEM PHARMA INC. (CA) 2001-08-14 US disclosed
EP-1115724-A1 QUINOLIZINONES AS INTEGRIN INHIBITORS Shire Biochem Inc. (CA) 2001-07-18 EP disclosed
WO-2000078723-A1 PROCESS FOR THE PREPARATION OF BUTOXYCARBONYLIMINO COMPOUNDS AND INTERMEDIATES THEREFOR GLAXO GROUP LIMITED (GB) 2000-12-28 WO disclosed
WO-2000078723-A1 PROCESS FOR THE PREPARATION OF BUTOXYCARBONYLIMINO COMPOUNDS AND INTERMEDIATES THEREFOR GLAXO GROUP LIMITED (GB) 2000-12-28 WO disclosed
WO-2000075129-A1 THIOPHENE INTEGRIN INHIBITORS SHIRE BIOCHEM INC. (CA) 2000-12-14 WO disclosed
WO-2000017197-A1 QUINOLIZINONES AS INTEGRIN INHIBITORS BIOCHEM PHARMA INC. (US) 2000-03-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115561-A1 BIPHENYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS CFTR, SCNN1B, SCNN1G RAB9A 769/4885ELANE 221/4885PCSK9 516/4885
US-20240239790-A1 7-Morpholino-1,6-Naphthyridin-5-yl Derivatives and Pharmaceutical Compositions Thereof Useful as DNA-PK Inhibitor DCK, ERCC2, POLK RAB9A 3740/4885ELANE 3995/4885PCSK9 3340/4885
US-20030087950-A1 New alpha-amino acid sulphonyl compounds DNPEP, DPP4, DPP7 RAB9A 1612/4885ELANE 985/4885PCSK9 3377/4885
US-12077543-B2 P2X3 and/or P2X2/3 compounds and methods P2RX3, P2RX6, P2RX2 RAB9A 2320/4885ELANE 2136/4885PCSK9 4727/4885
US-20240391925-A1 P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS P2RX3, P2RX6, P2RX2 RAB9A 2320/4885ELANE 2136/4885PCSK9 4727/4885
US-20240066135-A1 DRUG CONJUGATES AND USES THEREOF SLC7A1, ABCB11, SLC1A5 RAB9A 638/4885ELANE 1006/4885PCSK9 426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.