SCHEMBL17669100

SCHEMBL17669100

CCCCCCC(Cl)[SiH](OCC)OCC

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.38
LMNA P02545 1/20 0.35
DNM1 Q05193 2/20 0.34
SMPD1 P17405 3/20 0.33
TSHR P16473 1/20 0.33
THRB P10828 1/20 0.33
FDPS P14324 3/20 0.32
GPR84 Q9NQS5 2/20 0.32
ZDHHC7 Q9NXF8 1/20 0.32
SPHK1 Q9NYA1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17669051 0.98 OPRM1 (0.39) OPRM1LMNADNM1SMPD1FDPS
SCHEMBL17669034 0.91 DNM1 (0.32) OPRM1DNM1
SCHEMBL320815 0.82
SCHEMBL17669045 0.81 ZDHHC7 (0.37) OPRM1LMNADNM1SMPD1TSHR
SCHEMBL28058809 0.81 TSHR (0.31) TSHR
SCHEMBL17668935 0.78 OPRM1 (0.36) OPRM1LMNADNM1SMPD1TSHR
SCHEMBL28343743 0.78 OPRM1 (0.41) OPRM1LMNADNM1TSHRTHRB
SCHEMBL4735091 0.77 OPRM1 (0.44) OPRM1LMNADNM1SMPD1TSHR
SCHEMBL6298297 0.77 OPRM1 (0.44) OPRM1LMNADNM1SMPD1TSHR
SCHEMBL5574668 0.77 OPRM1 (0.44) OPRM1LMNADNM1SMPD1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3009439-B1 CYCLIC AMINOORGANOXYSILANE COMPOUND AND ITS PRODUCTION METHOD SHINETSU CHEMICAL CO (JP) 2018-01-03 EP disclosed
US-9371341-B2 Cyclic aminoorganoxysilane compound and its production method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-06-21 US disclosed
EP-3009439-A1 CYCLIC AMINOORGANOXYSILANE COMPOUND AND ITS PRODUCTION METHOD Shin-Etsu Chemical Co., Ltd. (JP) 2016-04-20 EP disclosed
US-20160102111-A1 CYCLIC AMINOORGANOXYSILANE COMPOUND AND ITS PRODUCTION METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-04-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160102111-A1 CYCLIC AMINOORGANOXYSILANE COMPOUND AND ITS PRODUCTION METHOD BCAT2, BCAT1, AKR1B10 OPRM1 323/4885LMNA 3625/4885DNM1 3942/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.