Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1836306 | 0.85 | NAPRT (0.53) | NAPRTLTA4HMAPK14MKNK1MKNK2 | |
| SCHEMBL27724284 | 0.83 | KDM4E (0.50) | NAPRTLTA4HMAPK14MKNK1MKNK2 | |
| SCHEMBL19475045 | 0.81 | MEN1 (0.39) | NAPRTMKNK1MKNK2RAB9AHTT | |
| SCHEMBL10723234 | 0.81 | LTA4H (0.47) | NAPRTLTA4HMAPK14MKNK1MKNK2 | |
| SCHEMBL5206688 | 0.81 | RAB9A (0.41) | NAPRTMKNK1MKNK2RAB9AMAPT | |
| SCHEMBL5309545 | 0.79 | TRIM24 (0.40) | NAPRTNPC1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL22497146 | 0.79 | SMN1; SMN2 (0.47) | NPC1RAB9AHTTSMN1; SMN2MEN1 | |
| SCHEMBL7626781 | 0.79 | MKNK1 (0.46) | MKNK1MKNK2MEN1KMT2APLAU | |
| SCHEMBL10569219 | 0.79 | LMNA (0.63) | NAPRTLTA4HMAPK14NPC1RAB9A | |
| SCHEMBL22583116 | 0.79 | ALDH1A1 (0.49) | NAPRTLTA4HMAPK14NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9658234-B2 | Method for analysis of compounds with amino group and analytical reagent therefor | AJINOMOTO CO., INC. (JP) | 2017-05-23 | — | — | US | disclosed |
| US-20160139134-A1 | METHOD FOR ANALYSIS OF COMPOUNDS WITH AMINO GROUP AND ANALYTICAL REAGENT THEREFOR | AJINOMOTO CO., INC. (JP) | 2016-05-19 | — | — | US | disclosed |
| US-9274123-B2 | Method for analysis of compounds with amino group and analytical reagent therefor | AJINOMOTO CO., INC. (JP) | 2016-03-01 | — | — | US | disclosed |
| EP-1475632-B1 | METHOD OF ANALYZING AMINOFUNCTIONAL COMPOUND AND ANALYTICAL REAGENT | AJINOMOTO KK (JP) | 2013-05-22 | — | — | EP | disclosed |
| EP-2336763-A1 | Method for analysis of compounds with amino group and analytical reagent thereof | Ajinomoto Co., Inc. (JP) | 2011-06-22 | — | — | EP | disclosed |
| EP-2317307-A2 | Method of analyzing amino- and/or imino-functional compounds, and analytical reagent | Ajinomoto Co., Inc. (JP) | 2011-05-04 | — | — | EP | disclosed |
| US-20060286673-A1 | Method for analysis of compounds with amino group and analytical reagent therefor | AJINOMOTO CO. INC (JP) | 2006-12-21 | — | — | US | disclosed |
| US-7148069-B2 | Method for analysis of compounds with amino group and analytical reagent therefor | AJINOMOTO CO., INC. (JP) | 2006-12-12 | — | — | US | disclosed |
| US-20050079624-A1 | Method for analysis of compounds with amino group and analytical reagent therefor | AJINOMOTO CO., INC (JP) | 2005-04-14 | — | — | US | disclosed |
| EP-1475632-A1 | METHOD OF ANALYZING AMINOFUNCTIONAL COMPOUND AND ANALYTICAL REAGENT | Ajinomoto Co., Inc. (JP) | 2004-11-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160139134-A1 | METHOD FOR ANALYSIS OF COMPOUNDS WITH AMINO GROUP AND ANALYTICAL REAGENT THEREFOR | CTH, VIP, SLC7A11 | NAPRT 2701/4885LTA4H 1691/4885MAPK14 3286/4885 |
| US-20050079624-A1 | Method for analysis of compounds with amino group and analytical reagent therefor | CTH, VIP, SLC7A11 | NAPRT 2701/4885LTA4H 1691/4885MAPK14 3286/4885 |
| US-20060286673-A1 | Method for analysis of compounds with amino group and analytical reagent therefor | CTH, VIP, SLC7A11 | NAPRT 2701/4885LTA4H 1691/4885MAPK14 3286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.