Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28121833 | 0.84 | PTGS1 (0.51) | CNR2ATML3MBTL1PPARGPPARA | |
| SCHEMBL11603067 | 0.82 | L3MBTL1 (0.59) | ATML3MBTL1KMT2AHPGDKDM4E | |
| SCHEMBL28444437 | 0.80 | ACP3 (0.51) | ATML3MBTL1PPARGPPARAIDO1 | |
| SCHEMBL28471244 | 0.78 | HDAC4 (0.53) | CNR2HDAC4HDAC7HDAC5CES2 | |
| SCHEMBL3711116 | 0.77 | SRC (0.58) | CNR2HDAC4HDAC7HDAC5IDO1 | |
| SCHEMBL28328822 | 0.76 | CES2 (0.43) | CNR2PPARGPPARAHDAC4HDAC7 | |
| SCHEMBL6439691 | 0.75 | SRC (0.61) | ATML3MBTL1KMT2AHPGDKDM4E | |
| SCHEMBL15645799 | 0.75 | MMP8 (0.50) | CNR2HDAC4HDAC7HDAC5CES2 | |
| SCHEMBL29002097 | 0.75 | KMT2A (0.56) | ATML3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL8122364 | 0.74 | ATM (0.54) | ATML3MBTL1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106795178-B | Substituted pyrimidinium compounds for controlling animal pests | 巴斯夫欧洲公司 | 2020-05-26 | — | — | CN | disclosed |
| EP-3204390-B1 | SUBSTITUTED PYRIMIDINIUM COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2019-06-05 | — | — | EP | disclosed |
| US-20170295791-A1 | SUBSTITUTED PYRIMIDINIUM COMPOUNDS FOR COMBATING ANIMAL PESTS | Basf India Limited (IN) | 2017-10-19 | — | — | US | disclosed |
| US-20170295791-A1 | SUBSTITUTED PYRIMIDINIUM COMPOUNDS FOR COMBATING ANIMAL PESTS | Basf India Limited (IN) | 2017-10-19 | — | — | US | disclosed |
| EP-3204390-A1 | SUBSTITUTED PYRIMIDINIUM COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2017-08-16 | — | — | EP | disclosed |
| WO-2016055431-A1 | SUBSTITUTED PYRIMIDINIUM COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2016-04-14 | — | — | WO | disclosed |
| WO-2016055431-A1 | SUBSTITUTED PYRIMIDINIUM COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2016-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170295791-A1 | SUBSTITUTED PYRIMIDINIUM COMPOUNDS FOR COMBATING ANIMAL PESTS | DDT, NPEPPS, PLPBP | CNR2 2055/4885ATM 3452/4885L3MBTL1 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.