Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 2/20 | 0.56 |
| ▸ | RARB | P10826 | 2/20 | 0.56 |
| ▸ | RARG | P13631 | 2/20 | 0.56 |
| ▸ | RXRA | P19793 | 9/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.32 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.32 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703988 | 0.84 | RARA (0.57) | RARARARBRARGRXRAPGR | |
| SCHEMBL7709931 | 0.82 | RARA (0.56) | RARARARBRARGRXRAPGR | |
| SCHEMBL6221699 | 0.82 | RARA (0.56) | RARARARBRARGRXRAPGR | |
| SCHEMBL9092549 | 0.80 | RARA (0.54) | RARARARBRARGRXRACASP3 | |
| SCHEMBL6222999 | 0.79 | RARA (0.56) | RARARARBRARGRXRAPGR | |
| SCHEMBL9091776 | 0.78 | RARA (0.51) | RARARARBRARGRXRAALDH1A1 | |
| SCHEMBL7710016 | 0.75 | RARA (0.57) | RARARARBRARGRXRAPGR | |
| SCHEMBL7703905 | 0.73 | RARA (0.56) | RARARARBRARGRXRAPGR | |
| SCHEMBL6227625 | 0.73 | RARA (0.55) | RARARARBRARGRXRAHDAC1 | |
| SCHEMBL6223133 | 0.73 | RARA (0.47) | RARARARBRARGRXRASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3496711-B1 | SYNTHETIC RETINOIDS (IN CELL MODULATION) | UNIV DURHAM (GB) | 2026-03-18 | — | — | EP | disclosed |
| CN-109843291-B | Synthetic retinoids (cell modulation) | 杜伦大学 | 2024-06-25 | — | — | CN | disclosed |
| US-11833203-B2 | Synthetic retinoids (in cell modulation) | UNIVERSITY OF DURHAM | 2023-12-05 | — | — | US | disclosed |
| US-11833203-B2 | Synthetic retinoids (in cell modulation) | UNIVERSITY OF DURHAM | 2023-12-05 | — | — | US | disclosed |
| US-11833203-B2 | Synthetic retinoids (in cell modulation) | UNIVERSITY OF DURHAM | 2023-12-05 | — | — | US | disclosed |
| US-11324825-B2 | Synthetic retinoids (in cell modulation) | UNIVERSITY OF DURHAM | 2022-05-10 | — | — | US | disclosed |
| US-11324825-B2 | Synthetic retinoids (in cell modulation) | UNIVERSITY OF DURHAM | 2022-05-10 | — | — | US | disclosed |
| EP-3204357-B1 | FLUORESCENT SYNTHETIC RETINOIDS | HIGH FORCE RES LIMITED (GB) | 2022-01-19 | — | — | EP | disclosed |
| EP-3204357-B1 | FLUORESCENT SYNTHETIC RETINOIDS | HIGH FORCE RES LIMITED (GB) | 2022-01-19 | — | — | EP | disclosed |
| CN-107250112-B | Fluorescent synthetic retinoids | 高力研究有限公司 | 2021-04-23 | — | — | CN | disclosed |
| US-20190209685-A1 | SYNTHETIC RETINOIDS (IN CELL MODULATION) | UNIVERSITY OF DURHAM (GB) | 2019-07-11 | — | — | US | disclosed |
| US-20190209684-A1 | Synthetic Retinoids (in Cell Modulation) | UNIVERSITY OF DURHAM (GB) | 2019-07-11 | — | — | US | disclosed |
| US-20190209684-A1 | Synthetic Retinoids (in Cell Modulation) | UNIVERSITY OF DURHAM (GB) | 2019-07-11 | — | — | US | disclosed |
| US-20190209685-A1 | SYNTHETIC RETINOIDS (IN CELL MODULATION) | UNIVERSITY OF DURHAM (GB) | 2019-07-11 | — | — | US | disclosed |
| WO-2018029473-A1 | SYNTHETIC RETINOIDS (IN CELL MODULATION) | UNIVERSITY OF DURHAM (GB) | 2018-02-15 | — | — | WO | disclosed |
| EP-3204357-A2 | FLUORESCENT SYNTHETIC RETINOIDS | High Force Research Limited (GB) | 2017-08-16 | — | — | EP | disclosed |
| US-20170217893-A1 | Fluorescent Synthetic Retinoids | HIGH FORCE RESEARCH LIMITED (GB) | 2017-08-03 | — | — | US | disclosed |
| US-20170217893-A1 | Fluorescent Synthetic Retinoids | HIGH FORCE RESEARCH LIMITED (GB) | 2017-08-03 | — | — | US | disclosed |
| US-20170217893-A1 | Fluorescent Synthetic Retinoids | HIGH FORCE RESEARCH LIMITED (GB) | 2017-08-03 | — | — | US | disclosed |
| WO-2016055800-A2 | FLUORESCENT SYNTHETIC RETINOIDS | HIGH FORCE RESEARCH LIMITED (GB) | 2016-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11833203-B2 | Synthetic retinoids (in cell modulation) | RARA, RARB, RXRA | RARA 1/4885RARB 2/4885RARG 4/4885 |
| US-11324825-B2 | Synthetic retinoids (in cell modulation) | RARA, RARB, RXRA | RARA 1/4885RARB 2/4885RARG 4/4885 |
| US-20190209685-A1 | SYNTHETIC RETINOIDS (IN CELL MODULATION) | RARA, RARB, RXRA | RARA 1/4885RARB 2/4885RARG 4/4885 |
| US-20170217893-A1 | Fluorescent Synthetic Retinoids | RARB, RXRB, RXRA | RARA 4/4885RARB 1/4885RARG 5/4885 |
| US-20190209684-A1 | Synthetic Retinoids (in Cell Modulation) | RARA, RARB, RXRA | RARA 1/4885RARB 2/4885RARG 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.