SCHEMBL17677095

SCHEMBL17677095

CC1(C)c2ccccc2-c2c1c1cc(-c3ccc4c(c3)c3c(n4-c4ccccc4)-c4ccccc4C3(C)C)ccc1n2-c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PGR P06401 6/20 0.38
▸ KDM4E B2RXH2 4/20 0.35
▸ L3MBTL1 Q9Y468 3/20 0.35
▸ ATM Q13315 1/20 0.35
▸ IL1R1 P14778 1/20 0.34
▸ MAPT P10636 3/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ HTT P42858 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ GAA P10253 1/20 0.32
▸ GFER P55789 1/20 0.32
▸ HPGD P15428 3/20 0.32
▸ HSD17B10 Q99714 2/20 0.32
▸ TSHR P16473 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ CASP1 P29466 1/20 0.32
▸ CASP7 P55210 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17677012 0.93 L3MBTL1 (0.43) PGRKDM4EL3MBTL1ATMIL1R1
SCHEMBL17677113 0.91 PGR (0.33) PGRL3MBTL1IL1R1MAPTMEN1
SCHEMBL17677021 0.91 PGR (0.33) PGRL3MBTL1IL1R1MAPTMEN1
SCHEMBL17677082 0.91 PGR (0.33) PGRGAAGFER
SCHEMBL17677083 0.89 PGR (0.32) PGRL3MBTL1IL1R1MAPTMEN1
SCHEMBL17677051 0.89 PGR (0.32) PGRL3MBTL1IL1R1MAPTMEN1
SCHEMBL15894388 0.89 RXRA (0.34) PGRL3MBTL1IL1R1MAPTMEN1
SCHEMBL17677076 0.88 TSPO (0.32) PGR
SCHEMBL17667116 0.87 L3MBTL1 (0.46) PGRKDM4EL3MBTL1ATMIL1R1
SCHEMBL15894417 0.87 MEN1 (0.36) PGRKDM4EL3MBTL1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3006426-B1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2019-01-09 — — EP disclosed
US-9985216-B2 Indenoindole derivative and organic electroluminescent element HODOGAYA CHEMICAL CO., LTD. (JP) 2018-05-29 — — US disclosed
US-9985216-B2 Indenoindole derivative and organic electroluminescent element HODOGAYA CHEMICAL CO., LTD. (JP) 2018-05-29 — — US disclosed
US-20160126468-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO., LTD. (JP) 2016-05-05 — — US disclosed
US-20160126468-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO., LTD. (JP) 2016-05-05 — — US disclosed
EP-3006426-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2016-04-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160126468-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT IDO2, SLCO2B1, IDO1 PGR 916/4885KDM4E 922/4885L3MBTL1 2737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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