SCHEMBL17680374

SCHEMBL17680374

CC(C)(c1ccc(-c2ccc(-n3c4ccccc4c4ncccc43)cc2)cc1)c1ccc(-n2c3ccccc3c3ncccc32)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.38
KDM4E B2RXH2 3/20 0.38
ATM Q13315 1/20 0.38
TOP1 P11387 3/20 0.34
COMT P21964 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
NPC1 O15118 1/20 0.33
HSP90AA1 P07900 1/20 0.33
HDAC4 P56524 1/20 0.33
PPARG P37231 4/20 0.33
PPARA Q07869 2/20 0.33
AKT1 P31749 2/20 0.32
AKT2 P31751 1/20 0.32
AKT3 Q9Y243 1/20 0.32
MAPK14 Q16539 1/20 0.32
KMT2A Q03164 1/20 0.32
KIF11 P52732 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL261528 0.96 KDM4E (0.41) L3MBTL1KDM4EATMCOMTALDH1A1
SCHEMBL15695210 0.94 KDM4E (0.43) L3MBTL1KDM4EATMCOMTALDH1A1
SCHEMBL261831 0.89 KDM4E (0.47) L3MBTL1KDM4EATMCOMTALDH1A1
SCHEMBL13141973 0.89 KDM4E (0.47) L3MBTL1KDM4EATMCOMTALDH1A1
SCHEMBL16769710 0.87 L3MBTL1 (0.34) L3MBTL1KDM4EATMCOMTNPC1
SCHEMBL12383130 0.87 KIF11 (0.38) TOP1MAPK14KIF11
SCHEMBL13811428 0.86 MAOA (0.39) L3MBTL1KDM4EATMCOMTALDH1A1
SCHEMBL17425807 0.85 HTT (0.33) L3MBTL1KDM4EATMCOMTALDH1A1
SCHEMBL16482263 0.84 L3MBTL1 (0.43) L3MBTL1KDM4EATMTOP1COMT
SCHEMBL16482566 0.84 KDM4E (0.53) L3MBTL1KDM4EATMALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9484541-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-11-01 US disclosed
US-9484541-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-11-01 US disclosed
US-20160111661-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-04-21 US disclosed
US-20160111661-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-04-21 US disclosed
US-20160104848-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-04-14 US disclosed
US-20160104848-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-04-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160111661-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, ZYX, LBR L3MBTL1 81/4885KDM4E 1495/4885ATM 3332/4885
US-20160104848-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ORC3, FARS2, FARSA L3MBTL1 1216/4885KDM4E 3162/4885ATM 3925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.