SCHEMBL16769710

SCHEMBL16769710

CC(C)(c1ccc(-n2c3ccccc3c3ncccc32)cc1)c1ccc(C(C)(C)n2c3ccccc3c3ncccc32)cc1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.34
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
PDE4A P27815 1/20 0.32
PDE4B Q07343 1/20 0.32
PDE4C Q08493 1/20 0.32
PDE4D Q08499 1/20 0.32
COMT P21964 1/20 0.31
PPARG P37231 3/20 0.31
PPARA Q07869 2/20 0.31
NPC1 O15118 1/20 0.30
HSP90AA1 P07900 1/20 0.30
AKT1 P31749 1/20 0.30
AKT2 P31751 1/20 0.30
AKT3 Q9Y243 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL261528 0.91 KDM4E (0.41) L3MBTL1KDM4EATMPDE4APDE4B
SCHEMBL15695210 0.90 KDM4E (0.43) L3MBTL1KDM4EATMPDE4APDE4B
SCHEMBL17680374 0.87 L3MBTL1 (0.38) L3MBTL1KDM4EATMCOMTPPARG
SCHEMBL13811428 0.84 MAOA (0.39) L3MBTL1KDM4EATMCOMTNPC1
SCHEMBL12113727 0.84 KDM4E (0.48) L3MBTL1KDM4EATMPPARGPPARA
SCHEMBL17425807 0.81 HTT (0.33) L3MBTL1KDM4EATMCOMTPPARG
SCHEMBL12383114 0.79 KCNH2 (0.36) L3MBTL1NPC1HSP90AA1AKT1AKT2
SCHEMBL23838485 0.78 KDM4E (0.30) L3MBTL1KDM4EATM
SCHEMBL21674421 0.76 KDM4E (0.48) L3MBTL1KDM4EATMPPARGPPARA
SCHEMBL11978685 0.76 ALDH1A1 (0.47) L3MBTL1KDM4EATMCOMTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10644251-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-05-05 US disclosed
US-20150155501-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-06-04 US disclosed
US-20150155501-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10644251-B2 Organic electroluminescent materials and devices RUVBL1, RUVBL2, LIFR L3MBTL1 97/4885KDM4E 3302/4885ATM 1265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.