Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | IDO1 | P14902 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | IDH2 | P48735 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31590848 | 0.84 | L3MBTL1 (0.54) | MAPTALDH1A1GAAIDO1RAB9A | |
| SCHEMBL29876277 | 0.84 | L3MBTL1 (0.54) | MAPTALDH1A1GAAIDO1RAB9A | |
| SCHEMBL11406613 | 0.82 | L3MBTL1 (0.53) | MAPTALDH1A1GAAIDO1RAB9A | |
| SCHEMBL14995940 | 0.81 | L3MBTL1 (0.65) | MAPTALDH1A1GAAIDO1RAB9A | |
| SCHEMBL11409430 | 0.81 | L3MBTL1 (0.51) | MAPTALDH1A1GAAIDO1RAB9A | |
| SCHEMBL30085693 | 0.79 | L3MBTL1 (0.50) | MAPTALDH1A1GAAIDO1RAB9A | |
| SCHEMBL125625 | 0.78 | ALDH1A1 (0.61) | MAPTALDH1A1GAAIDO1RAB9A | |
| SCHEMBL2925587 | 0.77 | MAPT (0.58) | MAPTALDH1A1GAAIDO1RAB9A | |
| SCHEMBL394991 | 0.77 | KIF11 (0.70) | MAPTALDH1A1GAARAB9ASMN1; SMN2 | |
| SCHEMBL29748950 | 0.77 | MAPT (0.58) | MAPTALDH1A1GAAIDO1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016057931-A1 | TRIFLUOROMETHOXYLATION OF ARENES VIA INTRAMOLECULAR TRIFLUOROMETHOXY GROUP MIGRATION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2016-04-14 | — | — | WO | disclosed |