Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | GAK | O14976 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | MARK1 | Q9P0L2 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9920689 | 0.84 | AXL (0.57) | AXLKEAP1APPRAB9AKIT | |
| SCHEMBL9052445 | 0.84 | MKNK1 (0.56) | RAB9AMKNK2MEN1NPC1KMT2A | |
| SCHEMBL17686764 | 0.83 | NOTUM (0.44) | AXLKEAP1APPRAB9A | |
| SCHEMBL31466033 | 0.81 | PDPK1 (0.42) | AXLKEAP1RAB9APOLBMAPT | |
| SCHEMBL17686763 | 0.81 | TNIK (0.44) | RAB9AMAPK1ATMNPC1KMT2A | |
| SCHEMBL14985510 | 0.75 | RAB9A (0.64) | AXLKEAP1APPRAB9AMAPK1 | |
| SCHEMBL1702207 | 0.73 | ALDH1A1 (0.67) | AXLKEAP1APPRAB9AKIT | |
| SCHEMBL5837879 | 0.73 | AXL (0.58) | AXLKEAP1APPRAB9AKIT | |
| SCHEMBL1608472 | 0.73 | RAB9A (0.62) | AXLKEAP1APPRAB9AMAPK1 | |
| SCHEMBL3488442 | 0.73 | AXL (0.62) | AXLKEAP1APPRAB9AKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408314-B | Process for preparing 3, 5-bis (fluoroalkyl) pyrazole derivatives from α -dihaloamines | 拜耳作物科学股份公司 | 2018-04-24 | — | — | CN | disclosed |
| EP-2999694-B1 | PROCESS FOR PREPARING 3,5-BIS(FLUOROALKYL)PYRAZOLE DERIVATIVES FROM ALPHA,ALPHA -DIHALOAMINES | BAYER CROPSCIENCE AG (DE) | 2017-05-17 | — | — | EP | disclosed |
| US-9512081-B2 | Process for preparing 3,5-bis(fluoroalkyl)pyrazole derivatives from α,α-dihaloamines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-12-06 | — | — | US | disclosed |
| US-20160108000-A1 | PROCESS FOR PREPARING 3,5-BIS(FLUOROALKYL)PYRAZOLE DERIVATIVES FROM a,a-DIHALOAMINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-04-21 | — | — | US | disclosed |
| CN-105408314-A | Process for preparing 3, 5-bis (fluoroalkyl) pyrazole derivatives from alpha, alpha-dihaloamines | BAYER CROPSCIENCE AG | 2016-03-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160108000-A1 | PROCESS FOR PREPARING 3,5-BIS(FLUOROALKYL)PYRAZOLE DERIVATIVES FROM a,a-DIHALOAMINES | HDHD5, CYP4F3, AADAC | AXL 2752/4885KEAP1 1020/4885APP 1381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.