SCHEMBL1769072

SCHEMBL1769072

CCC(C)(C)C1CC(C(=O)O)CC(C(=O)O)C1

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 2/20 0.35
GRM3 Q14832 1/20 0.35
GRM1 Q13255 2/20 0.33
APLNR P35414 1/20 0.32
S1PR5 Q9H228 1/20 0.32
POLB P06746 1/20 0.32
LMNA P02545 2/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GRM5 P41594 1/20 0.31
BTK Q06187 1/20 0.31
GABRR1 P24046 5/20 0.30
GABRR2 P28476 1/20 0.30
GAA P10253 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18628984 0.84 GRM2 (0.37) GRM2GRM3S1PR5LMNAALDH1A1
SCHEMBL14267477 0.83 GRM2 (0.35) GRM2GRM3GRM1APLNRPOLB
SCHEMBL11029634 0.79 LMNA (0.42) APLNRS1PR5POLBLMNAALDH1A1
SCHEMBL11023629 0.79 LMNA (0.42) APLNRS1PR5POLBLMNAALDH1A1
SCHEMBL1769081 0.78 APLNR (0.37) GRM2GRM1APLNRS1PR5POLB
SCHEMBL19645224 0.76 CHRNB2 (0.44) LMNAALDH1A1MAPTSMN1; SMN2GAA
SCHEMBL12384655 0.75 APLNR (0.39) GRM2GRM1APLNRS1PR5POLB
SCHEMBL12424332 0.75 APLNR (0.39) GRM2GRM1APLNRS1PR5POLB
SCHEMBL864032 0.73 APLNR (0.37) GRM2GRM1APLNRS1PR5POLB
SCHEMBL17803093 0.73 CES2 (0.37) GRM2GRM1APLNRPOLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013096373-A1 ALIPHATIC-AROMATIC COPOLYETHERESTERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-06-27 WO disclosed
US-20130158168-A1 ALIPHATIC-AROMATIC COPOLYETHERESTERS E I DU PONT DE NEMOURS AND COMPANY (US) 2013-06-20 US disclosed
US-20130158196-A1 ALIPHATIC-AROMATIC COPOLYETHERESTERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-06-20 US disclosed
US-8409677-B2 Biodegradable starch-containing blend E I DU PONT DE NEMOURS AND COMPANY (US) 2013-04-02 US disclosed
US-20110207859-A1 COPOLYESTERS WITH ENHANCED TEAR STRENGTH E.I.DU PONT DE NEMOURS AND COMPANY (US) 2011-08-25 US disclosed
WO-2011091130-A1 BIODEGRADABLE STARCH-CONTAINING BLEND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-28 WO disclosed
US-20110177275-A1 BIODEGRADABLE STARCH-CONTAINING BLEND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-21 US disclosed
WO-2011062600-A1 POLYCONDENSATION WITH A KNEADER REACTOR E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-05-26 WO disclosed
WO-2010075023-A1 COPOLYESTERS WITH ENHANCED TEAR STRENGTH E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-01 WO disclosed