Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 13/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 13/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNB3 | Q05901 | 2/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.32 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1769472 | 0.82 | CHRNB2 (0.54) | CHRNB2CHRNA4CHRNA3CHRNB1CHRNB4 | |
| SCHEMBL1769195 | 0.82 | CHRNB2 (0.54) | CHRNB2CHRNA4CHRNA3CHRNB1CHRNB4 | |
| SCHEMBL1769225 | 0.73 | CHRNB2 (0.42) | CHRNB2CHRNA4CHRNA3CHRNB4DRD2 | |
| SCHEMBL14776776 | 0.72 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA3CHRNB1CHRNB4 | |
| SCHEMBL14776666 | 0.72 | CHRNB2 (0.97) | CHRNB2CHRNA4CHRNA3CHRNB1CHRNB4 | |
| SCHEMBL25344779 | 0.71 | NFE2L2 (0.54) | CHRNB2CHRNA4 | |
| SCHEMBL14776261 | 0.71 | CHRNB2 (0.97) | CHRNB2CHRNA4CHRNA3CHRNB1CHRNB4 | |
| SCHEMBL14776556 | 0.70 | CHRNB2 (0.72) | CHRNB2CHRNA4CHRNA3CHRNB1CHRNB4 | |
| SCHEMBL23634063 | 0.70 | NCF1 (0.47) | — | |
| SCHEMBL14776559 | 0.69 | CHRNB2 (0.70) | CHRNB2CHRNA4CHRNA3CHRNB1CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513085-A1 | BICYCLIC COMPOUNDS AS alpha4beta2 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | Suven Life Sciences Limited (IN) | 2012-10-24 | — | — | EP | claimed |
| WO-2011061751-A1 | BICYCLIC COMPOUNDS AS α4β2 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-05-26 | — | — | WO | claimed |
| EP-2513085-A1 | BICYCLIC COMPOUNDS AS alpha4beta2 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | Suven Life Sciences Limited (IN) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011061751-A1 | BICYCLIC COMPOUNDS AS α4β2 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-05-26 | — | — | WO | disclosed |