Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | TPO | P07202 | 1/20 | 0.38 |
| ▸ | EPX | P11678 | 1/20 | 0.38 |
| ▸ | LPO | P22079 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9111641 | 0.82 | PARP15 (0.49) | MCHR1CHRNB2CHRNA4CYP4F2CYP4A11 | |
| SCHEMBL23634063 | 0.81 | NCF1 (0.47) | MPOTPOEPXLPO | |
| SCHEMBL15918434 | 0.79 | CHRNB2 (0.48) | NFE2L2CHRNB2CHRNA4IDO1ACACB | |
| SCHEMBL2562093 | 0.78 | NFE2L2 (0.83) | NFE2L2MCHR1ACACBAPP | |
| SCHEMBL25396199 | 0.78 | GPR119 (0.58) | BACE1 | |
| SCHEMBL31132814 | 0.76 | PARP10 (0.51) | MCHR1ACACB | |
| SCHEMBL23634060 | 0.76 | NCF1 (0.56) | MPOTPOEPXLPOAPP | |
| SCHEMBL16838830 | 0.76 | NFE2L2 (0.43) | NFE2L2ACACBCYP4F2CYP4A11LNPEP | |
| SCHEMBL28067029 | 0.75 | PARP10 (0.53) | NFE2L2MCHR1 | |
| SCHEMBL1920453 | 0.74 | RAB9A (0.54) | MCHR1MPOTPOEPXLPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4225746-A1 | MRGX2 ANTAGONISTS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022073904-A1 | MRGX2 ANTAGONISTS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2022-04-14 | — | — | WO | disclosed |