Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21134115 | 0.91 | ESR1 (0.38) | ESR1ESR2ALOX5AP | |
| SCHEMBL20806210 | 0.85 | ESR1 (0.34) | ESR1ESR2ALOX5AP | |
| SCHEMBL19120288 | 0.81 | ESR1 (0.32) | ESR1ESR2 | |
| SCHEMBL16265323 | 0.76 | ESR1 (0.34) | ESR1ESR2 | |
| SCHEMBL17694361 | 0.70 | ESR1 (0.30) | ESR1ESR2 | |
| SCHEMBL20806198 | 0.70 | ESR1 (0.37) | ESR1ESR2ALOX5AP | |
| SCHEMBL19369162 | 0.70 | ESR2 (0.46) | ESR1ESR2 | |
| SCHEMBL26500096 | 0.69 | HSD17B1 (0.42) | ESR1ESR2 | |
| SCHEMBL20806237 | 0.69 | ESR2 (0.45) | ESR1ESR2 | |
| SCHEMBL25070478 | 0.67 | ESR1 (0.40) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160108317-A1 | DEVICE FOR CONTROLLING THE PASSAGE OF ENERGY, CONTAINING A DICHROIC DYE COMPOUND | MERCK PATENT GMBH (DE) | 2016-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160108317-A1 | DEVICE FOR CONTROLLING THE PASSAGE OF ENERGY, CONTAINING A DICHROIC DYE COMPOUND | CRY1, SLC25A1, CRY2 | ESR1 2151/4885ESR2 2050/4885ALOX5AP 4659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.