Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12663220 | 0.91 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTGPR119 | |
| SCHEMBL1888484 | 0.91 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPT | |
| SCHEMBL29881025 | 0.91 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPT | |
| SCHEMBL13651528 | 0.89 | — | — | |
| SCHEMBL1886952 | 0.86 | — | — | |
| SCHEMBL29881798 | 0.86 | — | — | |
| SCHEMBL12527408 | 0.84 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTGPR119 | |
| SCHEMBL27983379 | 0.83 | HTR1A (0.54) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1769397 | 0.82 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTGPR119 | |
| SCHEMBL17251233 | 0.82 | SLC6A2 (0.53) | HTR1ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121649-B1 | Method for the production of benzofuran-2-carboxamides | MERCK PATENT GMBH (DE) | 2013-02-27 | — | — | EP | claimed |
| CN-101573347-B | Process for preparing benzofuran-2-carboxamides | MERCK PATENT GMBH | 2012-10-10 | — | — | CN | claimed |
| US-20100036139-A1 | PROCESS FOR THE PREPARATION OF BENZOFURAN-2-CARBOXAMIDES | MERCK PATENT GMBH (DE) | 2010-02-11 | — | — | US | claimed |
| EP-2121649-A1 | METHOD FOR THE PRODUCTION OF BENZOFURAN-2-CARBOXAMIDES | Merck Patent GmbH (DE) | 2009-11-25 | — | — | EP | claimed |
| CN-101573347-A | Process for preparing benzofuran-2-carboxamides | MERCK PATENT GMBH (DE) | 2009-11-04 | — | — | CN | claimed |
| WO-2008080456-A1 | METHOD FOR THE PRODUCTION OF BENZOFURAN-2-CARBOXAMIDES | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | WO | claimed |
| CN-1181067-C | Benzofurans | Ĭ��ר���ɷ�����˾ | 2004-12-22 | — | — | CN | claimed |
| EP-0738722-B1 | 5-Amino-benzofuran-2-carboxylic acid derivatives | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | claimed |
| CN-1140171-A | Benzofurans | MERCK PATENT GMBH (DE) | 1997-01-15 | — | — | CN | claimed |
| EP-0738722-A1 | 5-Amino-benzofuran-2-carboxylic acid derivatives | MERCK PATENT GmbH (DE) | 1996-10-23 | — | — | EP | claimed |
| CN-110092778-B | Method for preparing vilazodone intermediate and vilazodone medicine by using cheap metal copper | 浙江工业大学 | 2021-02-09 | — | — | CN | disclosed |
| US-20180002305-A1 | PROCESS FOR PREPARING BENZOFURAN-2-CARBOXAMIDE DERIVATIVES | SYMED LABS LIMITED (IN) | 2018-01-04 | — | — | US | disclosed |
| US-9796695-B2 | Process for preparing benzofuran-2-carboxamide derivatives | SYMED LABS LIMITED (IN) | 2017-10-24 | — | — | US | disclosed |
| US-20170267655-A1 | PROCESS FOR PREPARING BENZOFURAN-2-CARBOXAMIDE DERIVATIVES | SYMED LABS LIMITED (IN) | 2017-09-21 | — | — | US | disclosed |
| US-9682946-B2 | Process for preparing benzofuran-2-carboxamide derivatives | SYMED LABS LIMITED (IN) | 2017-06-20 | — | — | US | disclosed |
| WO-2001040219-A2 | METHOD FOR PRODUCING 5-(1-PIPERAZINYL)-BENZOFURAN-2-CARBOXAMIDE BY TRANSITION METAL-CATALYZED AMINATION | MERCK PATENT GMBH (DE) | 2001-06-07 | — | — | WO | disclosed |
| US-5977112-A | Process of making substituted benzofurans | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-11-02 | — | — | US | disclosed |
| US-5723614-A | Benzofurans | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-03-03 | — | — | US | disclosed |
| CN-1140171-A | Benzofurans | MERCK PATENT GMBH (DE) | 1997-01-15 | — | — | CN | disclosed |
| EP-0738722-A1 | 5-Amino-benzofuran-2-carboxylic acid derivatives | MERCK PATENT GmbH (DE) | 1996-10-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180002305-A1 | PROCESS FOR PREPARING BENZOFURAN-2-CARBOXAMIDE DERIVATIVES | HTR3C, VIL1, HTR4 | ALDH1A1 329/4885LMNA 1710/4885MAPT 1828/4885 |
| US-20170267655-A1 | PROCESS FOR PREPARING BENZOFURAN-2-CARBOXAMIDE DERIVATIVES | HTR3C, VIL1, HTR4 | ALDH1A1 329/4885LMNA 1710/4885MAPT 1828/4885 |
| US-20100036139-A1 | PROCESS FOR THE PREPARATION OF BENZOFURAN-2-CARBOXAMIDES | CCNT1, CCNT2, CBR1 | ALDH1A1 396/4885LMNA 2166/4885MAPT 2936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.