SCHEMBL17696288

SCHEMBL17696288

C=C(C)C(=O)OCCOCCNC(=O)OCCc1ccc(O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.47
LMNA P02545 1/20 0.47
KDM4E B2RXH2 1/20 0.44
F13A1 P00488 1/20 0.44
THRB P10828 1/20 0.43
MAPT P10636 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
OPRM1 P35372 1/20 0.40
OPRD1 P41143 1/20 0.40
OPRK1 P41145 1/20 0.40
MET P08581 4/20 0.39
TYR P14679 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13577810 0.95 KDM4E (0.47) SMN1; SMN2LMNAKDM4EF13A1THRB
SCHEMBL17034355 0.87 ALDH1A1 (0.47) SMN1; SMN2LMNAKDM4ETHRBMAPT
SCHEMBL17034217 0.87 ALDH1A1 (0.47) SMN1; SMN2LMNAKDM4ETHRBMAPT
SCHEMBL1119186 0.85 NPC1 (0.51) SMN1; SMN2KDM4EF13A1THRBMAPT
SCHEMBL13567313 0.85 KMT2A (0.43) SMN1; SMN2LMNATHRBNPC1RAB9A
SCHEMBL22035555 0.84 THRB (0.59) SMN1; SMN2LMNATHRBKMT2AALDH1A1
SCHEMBL24788342 0.82 L3MBTL1 (0.41) SMN1; SMN2LMNATHRBMAPTGLA
SCHEMBL17034210 0.82 ALDH1A1 (0.50) SMN1; SMN2LMNAKDM4EMAPTNPC1
SCHEMBL17034233 0.82 POLB (0.49) SMN1; SMN2LMNAKDM4ETHRBMAPT
SCHEMBL17034364 0.82 POLB (0.49) SMN1; SMN2LMNAKDM4ETHRBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11072741-B2 Optically anisotropic layer, method for producing the optically anisotropic layer, a laminate, polarizing plate, display device, liquid crystal compound, method for producing the liquid crystal compound, and carboxylic acid compound FUJIFILM CORPORATION (JP) 2021-07-27 US disclosed
US-20160108315-A1 OPTICALLY ANISOTROPIC LAYER, METHOD FOR PRODUCING THE OPTICALLY ANISOTROPIC LAYER, A LAMINATE, POLARIZING PLATE, DISPLAY DEVICE, LIQUID CRYSTAL COMPOUND, METHOD FOR PRODUCING THE LIQUID CRYSTAL COMPOUND, AND CARBOXYLIC ACID COMPOUND FUJIFILM CORPORATION (JP) 2016-04-21 US disclosed