SCHEMBL24788342

SCHEMBL24788342

C=C(C)C(=O)OCCNC(=O)OCCc1ccc(NC)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
GLA P06280 1/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 3/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TSHR P16473 2/20 0.37
THRB P10828 1/20 0.37
PKM P14618 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HTT P42858 3/20 0.36
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA4 P43681 1/20 0.36
ACHE P22303 1/20 0.35
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24788142 0.89 THRB (0.45) SMN1; SMN2TSHRTHRBALDH1A1HTT
SCHEMBL24788144 0.89 SMN1; SMN2 (0.51) L3MBTL1KMT2ALMNASMN1; SMN2TSHR
SCHEMBL13577810 0.87 KDM4E (0.47) L3MBTL1GLAKMT2ALMNASMN1; SMN2
SCHEMBL13567313 0.87 KMT2A (0.43) L3MBTL1GLAKMT2ALMNASMN1; SMN2
SCHEMBL17034210 0.85 ALDH1A1 (0.50) L3MBTL1GLAKMT2ALMNASMN1; SMN2
SCHEMBL17696288 0.82 SMN1; SMN2 (0.47) L3MBTL1GLAKMT2ALMNASMN1; SMN2
SCHEMBL24788140 0.82 L3MBTL1 (0.41) L3MBTL1GLAKMT2ALMNASMN1; SMN2
SCHEMBL17034217 0.82 ALDH1A1 (0.47) L3MBTL1GLAKMT2ALMNASMN1; SMN2
SCHEMBL17034355 0.82 ALDH1A1 (0.47) L3MBTL1GLAKMT2ALMNASMN1; SMN2
SCHEMBL13577775 0.81 MAPT (0.50) KMT2ALMNASMN1; SMN2TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795270-B2 Triazine ring-containing polymer and film forming composition containing same NISSAN CHEMICAL CORPORATION (JP) 2023-10-24 US disclosed
US-20230002555-A1 TRIAZINE RING-CONTAINING POLYMER AND FILM FORMING COMPOSITION CONTAINING SAME NISSAN CHEMICAL CORPORATION (JP) 2023-01-05 US disclosed
US-20220396666-A1 TRIAZINE RING-CONTAINING POLYMER AND FILM FORMING COMPOSITION CONTAINING SAME NISSAN CHEMICAL CORPORATION (JP) 2022-12-15 US disclosed