Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4138868 | 0.90 | NPSR1 (0.55) | ALDH1A1NPC1RAB9ANPSR1HTT | |
| SCHEMBL1769746 | 0.89 | NPSR1 (0.53) | ALDH1A1NPC1RAB9ANPSR1HTT | |
| SCHEMBL10596450 | 0.89 | NPSR1 (0.53) | ALDH1A1NPC1RAB9ANPSR1HTT | |
| SCHEMBL8854160 | 0.83 | RAB9A (0.61) | ALDH1A1NPC1RAB9ANPSR1HTT | |
| SCHEMBL9471405 | 0.83 | ALDH1A1 (0.61) | ALDH1A1NPC1RAB9ANPSR1HTT | |
| SCHEMBL28304342 | 0.82 | CA2 (0.44) | ALDH1A1NPC1RAB9ANPSR1HTT | |
| SCHEMBL830792 | 0.82 | ALDH1A1 (0.59) | ALDH1A1NPC1RAB9ANPSR1HTT | |
| SCHEMBL6673813 | 0.81 | NPSR1 (0.63) | ALDH1A1NPC1RAB9ANPSR1HTT | |
| SCHEMBL7385251 | 0.81 | KMT2A (0.50) | ALDH1A1NPC1RAB9ANPSR1POLB | |
| SCHEMBL629972 | 0.79 | NPSR1 (0.61) | ALDH1A1NPC1RAB9ANPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425904-A | Supported Ziegler-Natta catalyst and preparation method and application thereof | 山东京博石油化工有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-114316447-A | TPV material for vehicle and preparation method and application thereof | 东风汽车集团股份有限公司 | 2022-04-12 | — | — | CN | claimed |
| EP-1453789-A2 | N,N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | Elan Pharmaceuticals, Inc. (US) | 2004-09-08 | — | — | EP | claimed |
| WO-2003040096-A2 | N, N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | ELAN PHARMACEUTICALS, INC. (US) | 2003-05-15 | — | — | WO | claimed |
| CN-116425904-A | Supported Ziegler-Natta catalyst and preparation method and application thereof | 山东京博石油化工有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-114316447-B | TPV material for vehicle and preparation method and application thereof | 东风汽车集团股份有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-114316447-A | TPV material for vehicle and preparation method and application thereof | 东风汽车集团股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-107841036-B | Polypropylene composition, polypropylene material and application thereof | 中国石油化工股份有限公司 | 2020-06-30 | — | — | CN | disclosed |
| CN-107841054-B | Polypropylene composition, polypropylene material and application thereof | 中国石油化工股份有限公司 | 2020-06-30 | — | — | CN | disclosed |
| WO-2019005563-A1 | METHODS RELATED TO ACTIVATION OF THE BONE MORPHOGENIC PROTEIN SIGNALING PATHWAY | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2019-01-03 | — | — | WO | disclosed |
| CN-105566746-B | A kind of polypropene composition and polypropylene material and its application | 中国石油化工股份有限公司 | 2018-07-06 | — | — | CN | disclosed |
| CN-107841036-A | A kind of polypropene composition and polypropylene material and its application | 中国石油化工股份有限公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-107841054-A | A kind of polypropene composition and polypropylene material and its application | 中国石油化工股份有限公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-107312239-A | A kind of polypropene composition and polypropylene material | 中国石油化工股份有限公司 | 2017-11-03 | — | — | CN | disclosed |
| CN-104558821-B | A kind of polypropene composition and polypropylene material and its application | 中国石油化工股份有限公司 | 2017-08-11 | — | — | CN | disclosed |
| US-7727997-B2 | N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives | ELAN PHARMACEUTICALS, INC. (US) | 2010-06-01 | — | — | US | disclosed |
| US-20090131657-A1 | PROCESS FOR ALKENYLATING CARBOXAMIDES | BASF SE (DE) | 2009-05-21 | — | — | US | disclosed |
| US-20070213316-A1 | Compounds that are effective inhibitors of beta-secretase; inhibitors of beta-secretase-mediated cleavage of amyloid precursor proteins; effective inhibitors of A beta production, and/or are effective to reduce amyloid beta deposits or plaques; treatment of disorders such as Alzheimer's Disease | ELAN PHARMACEUTICALS, INC. | 2007-09-13 | — | — | US | disclosed |
| US-7176242-B2 | N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives | ELAN PHARMACEUTICALS, INC. (US) | 2007-02-13 | — | — | US | disclosed |
| EP-0155194-A2 | Thermoplastic resin compositions having improved moldability | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1985-09-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213316-A1 | Compounds that are effective inhibitors of beta-secretase; inhibitors of beta-secretase-mediated cleavage of amyloid precursor proteins; effective inhibitors of A beta production, and/or are effective to reduce amyloid beta deposits or plaques; treatment of disorders such as Alzheimer's Disease | BACE1, BACE2, APP | ALDH1A1 2133/4885NPC1 593/4885RAB9A 874/4885 |
| US-20090131657-A1 | PROCESS FOR ALKENYLATING CARBOXAMIDES | PRMT5, CYC1, CBR3 | ALDH1A1 1506/4885NPC1 3667/4885RAB9A 3925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.