SCHEMBL4138868

SCHEMBL4138868

NC(=O)CCCCC(=O)N(c1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.55
ALDH1A1 P00352 2/20 0.55
NPC1 O15118 1/20 0.55
POLB P06746 1/20 0.55
HTT P42858 1/20 0.55
RAB9A P51151 1/20 0.55
KMT2A Q03164 1/20 0.55
TRPM8 Q7Z2W7 1/20 0.43
ALOX5 P09917 5/20 0.42
TP53 P04637 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
ATM Q13315 1/20 0.40
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
CACNA2D1 P54289 1/20 0.39
CACNA1B Q00975 1/20 0.39
CACNB1 Q02641 1/20 0.39
CACNA1C Q13936 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1769746 0.98 NPSR1 (0.53) NPSR1ALDH1A1NPC1POLBHTT
SCHEMBL10596450 0.98 NPSR1 (0.53) NPSR1ALDH1A1NPC1POLBHTT
SCHEMBL6673813 0.92 NPSR1 (0.63) NPSR1ALDH1A1NPC1POLBHTT
SCHEMBL3350100 0.90 ALDH1A1 (0.57) NPSR1ALDH1A1NPC1POLBHTT
SCHEMBL17131834 0.90 NPSR1 (0.61) NPSR1ALDH1A1NPC1POLBHTT
SCHEMBL629972 0.90 NPSR1 (0.61) NPSR1ALDH1A1NPC1POLBHTT
SCHEMBL547693 0.85 NPSR1 (0.55) NPSR1ALDH1A1NPC1POLBHTT
SCHEMBL629973 0.85 NPSR1 (0.55) NPSR1ALDH1A1NPC1POLBHTT
SCHEMBL3242812 0.84 ALDH1A1 (0.40) NPSR1ALDH1A1NPC1POLBHTT
SCHEMBL16369620 0.84 ALDH1A1 (0.40) NPSR1ALDH1A1NPC1POLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116425904-A Supported Ziegler-Natta catalyst and preparation method and application thereof 山东京博石油化工有限公司 2023-07-14 CN claimed
CN-113316607-A Fiber sheet and method for producing same 花王株式会社 2021-08-27 CN claimed
CN-105968559-B The preparation method of crystal type thermoplastic resin based composite material 四川大学 2018-07-13 CN claimed
CN-104610695-B A kind of preparation method of Polypropylene structural wall pipe modified master 佛山顾地塑胶有限公司 2017-06-16 CN claimed
CN-105968559-A Preparation method of crystalline-thermoplastic-resin-base composite material 四川大学 2016-09-28 CN claimed
JP-59124950-A None JP disclosed
CN-119060535-A Polyamide composition and preparation method and application thereof 金发科技股份有限公司 2024-12-03 CN disclosed
WO-2023171155-A1 RESIN COMPOSITION FOR SEALANT FILM, SEALANT FILM, MULTILAYERED FILM, AND METHOD FOR PRODUCING SEALANT FILM 住友化学株式会社 2023-09-14 WO disclosed
CN-113316607-B Fiber sheet and method for producing same 花王株式会社 2023-07-28 CN disclosed
CN-116425904-A Supported Ziegler-Natta catalyst and preparation method and application thereof 山东京博石油化工有限公司 2023-07-14 CN disclosed
CN-113316607-A Fiber sheet and method for producing same 花王株式会社 2021-08-27 CN disclosed
CN-107841054-B Polypropylene composition, polypropylene material and application thereof 中国石油化工股份有限公司 2020-06-30 CN disclosed
US-20090131657-A1 PROCESS FOR ALKENYLATING CARBOXAMIDES BASF SE (DE) 2009-05-21 US disclosed
EP-1226209-A1 A COMBINATION OF A SOLID SOLVENT AND A MELT-PROCESSIBLE BLOCK COPOLYMER Gore Enterprise Holdings, Inc. (US) 2002-07-31 EP disclosed
WO-2001032763-A1 A COMBINATION OF A SOLID SOLVENT AND A MELT-PROCESSIBLE BLOCK COPOLYMER GORE ENTERPRISE HOLDINGS, INC. (US) 2001-05-10 WO disclosed
EP-0115218-B1 POLYPHENYLENE ETHER COMPOSITIONS HAVING IMPROVED PROCESSABILITY MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1989-10-18 EP disclosed
EP-0155194-B1 THERMOPLASTIC RESIN COMPOSITIONS HAVING IMPROVED MOLDABILITY MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1989-06-07 EP disclosed
EP-0155194-A2 Thermoplastic resin compositions having improved moldability MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1985-09-18 EP disclosed
EP-0115218-A2 Polyphenylene ether compositions having improved processability MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1984-08-08 EP disclosed
JP-S59124950-A POLYPHENYLENE ETHER RESIN COMPOSITION MITSUBISHI PETROCHEM CO LTD 1984-07-19 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090131657-A1 PROCESS FOR ALKENYLATING CARBOXAMIDES PRMT5, CYC1, CBR3 NPSR1 3299/4885ALDH1A1 1506/4885NPC1 3667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.