Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 9/20 | 0.43 |
| ▸ | LPL | P06858 | 8/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1701553 | 0.88 | LPL (0.44) | LIPGLPLIRAK4ADRA2CROCK1 | |
| SCHEMBL1726528 | 0.88 | LPL (0.44) | LIPGLPLIRAK4ADRA2CROCK1 | |
| SCHEMBL3762658 | 0.87 | LPL (0.43) | LIPGLPLIRAK4ADRA2CROCK1 | |
| SCHEMBL2192867 | 0.87 | LPL (0.43) | LIPGLPLIRAK4ADRA2CROCK1 | |
| SCHEMBL2940900 | 0.85 | ADRA2C (0.51) | LIPGLPLADRA2CHTR3A | |
| SCHEMBL31298214 | 0.85 | ADRA2C (0.51) | LIPGLPLADRA2CHTR3A | |
| SCHEMBL856181 | 0.85 | LMNA (0.46) | LIPGLPL | |
| SCHEMBL29790026 | 0.85 | LMNA (0.46) | LIPGLPL | |
| SCHEMBL14321720 | 0.85 | FAAH (0.41) | LIPGLPL | |
| SCHEMBL15464977 | 0.84 | ADRB1 (0.53) | ADRB1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723741-B1 | SUBSTITUTED IMIDAZOPYRIDINYL-AMINOPYRIDINE COMPOUNDS | ARQULE INC (US) | 2016-04-27 | — | — | EP | disclosed |