Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7570749 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL17698593 | 0.69 | NPC1 (0.35) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL3683321 | 0.69 | ALDH1A1 (0.41) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL8594297 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL8595956 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL8597663 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL2482252 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL2860865 | 0.64 | LMNA (0.33) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL8679012 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL4078640 | 0.62 | CYP11B1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1473323-B1 | Polyethylene composition and process for producing same | TOSOH CORP (JP) | 2016-04-27 | — | — | EP | disclosed |