Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7807237 | 0.85 | CYP3A4 (0.30) | — | |
| Hydrochloric Acid SCHEMBL6898339 | 0.81 | CYP1A2 (0.41) | — | |
| Hydrochloric Acid SCHEMBL8158883 | 0.76 | TLR8 (0.32) | — | |
| Hydrochloric Acid SCHEMBL7807224 | 0.76 | PTPN1 (0.35) | CYP11B2 | |
| Hydrochloric Acid SCHEMBL4078644 | 0.76 | HTR6 (0.34) | — | |
| Hydrochloric Acid SCHEMBL28553655 | 0.72 | GAA (0.33) | — | |
| Hydrochloric Acid SCHEMBL7807249 | 0.72 | CYP1A2 (0.34) | — | |
| Hydrochloric Acid SCHEMBL8170295 | 0.71 | TSHR (0.30) | — | |
| SCHEMBL8615005 | 0.70 | CNR2 (0.33) | CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL7196886 | 0.70 | CYP1A2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010051698-A1 | Highly active supported catalyst compositions | EXXONMOBIL CHEMICAL PATENTS INC. | 2001-12-13 | — | — | US | claimed |
| US-7521507-B2 | Polypropylene-based adhesive compositions | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-04-21 | — | — | US | disclosed |
| US-6524988-B2 | Metallocene, an activator and a fluorided support; polymerization catalyst | EXXONMOBIL CHEMICAL PATENTS INC. | 2003-02-25 | — | — | US | disclosed |
| US-20010051698-A1 | Highly active supported catalyst compositions | EXXONMOBIL CHEMICAL PATENTS INC. | 2001-12-13 | — | — | US | disclosed |