Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19931370 | 0.84 | GPR119 (0.33) | FYNMAP4K4MINK1TNIKKDM4E | |
| SCHEMBL14243224 | 0.81 | NOS3 (0.43) | KDM4EMAPTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16248181 | 0.77 | HSP90AA1 (0.40) | ALDH1A1CYP3A4CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL14706959 | 0.76 | PTGS2 (0.37) | PIK3CDPIP5K1CPIK3CBPI4KAPIK3CG | |
| SCHEMBL12549572 | 0.76 | PIK3CD (0.31) | PIK3CDPIP5K1CPIK3CBPI4KAPIK3CG | |
| SCHEMBL18594441 | 0.74 | NOS3 (0.40) | PIK3CDPIP5K1CPIK3CBPI4KAPIK3CG | |
| SCHEMBL16651152 | 0.74 | FYN (0.32) | FYNMAP4K4MINK1TNIKPIK3CD | |
| SCHEMBL27935057 | 0.72 | PIK3CD (0.31) | PIK3CDPIP5K1CPIK3CBPI4KAPIK3CG | |
| SCHEMBL1458885 | 0.72 | GAA (0.32) | ALDH1A1MEN1KMT2APIK3CDPIP5K1C | |
| SCHEMBL3257964 | 0.72 | UHRF1 (0.52) | FYNMAP4K4MINK1TNIKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160115158-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | ACTIVE BIOTECH AB (SE) | 2016-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160115158-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | S100A9, S100A4, S100B | FYN 1221/4885MAP4K4 2403/4885MINK1 1391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.