Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 10/20 | 0.63 |
| ▸ | ACHE | P22303 | 10/20 | 0.63 |
| ▸ | G6PD | P11413 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17722483 | 0.83 | BCHE (0.64) | BCHEACHEG6PDALDH1A1KDM4E | |
| SCHEMBL17718253 | 0.78 | ACHE (0.57) | BCHEACHEG6PDALDH1A1DNMT1 | |
| SCHEMBL6954550 | 0.78 | ACHE (1.00) | BCHEACHEG6PDALDH1A1 | |
| SCHEMBL28412674 | 0.78 | PAX8 (0.46) | BCHEACHEALDH1A1KDM4EGAA | |
| SCHEMBL8434517 | 0.77 | BCHE (0.72) | BCHEACHEG6PD | |
| SCHEMBL6964287 | 0.75 | BCHE (0.59) | BCHEACHEG6PD | |
| SCHEMBL6956970 | 0.73 | BCHE (0.65) | BCHEACHEG6PDALDH1A1GAA | |
| SCHEMBL15618825 | 0.72 | ALDH1A1 (0.60) | ALDH1A1KDM4E | |
| SCHEMBL6959190 | 0.71 | BCHE (0.83) | BCHEACHEG6PDALDH1A1GAA | |
| SCHEMBL29462463 | 0.71 | ALDH1A1 (0.46) | BCHEACHEALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160122383-A1 | Peptide Ligation | THE UNIVERSITY OF SYDNEY (AU) | 2016-05-05 | — | — | US | disclosed |
| US-20160122383-A1 | Peptide Ligation | THE UNIVERSITY OF SYDNEY (AU) | 2016-05-05 | — | — | US | disclosed |
| US-20160122383-A1 | Peptide Ligation | THE UNIVERSITY OF SYDNEY (AU) | 2016-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160122383-A1 | Peptide Ligation | PTMS, PTMA, QPCTL | BCHE 1323/4885ACHE 3052/4885G6PD 4712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.