Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 10/20 | 0.59 |
| ▸ | ACHE | P22303 | 10/20 | 0.59 |
| ▸ | G6PD | P11413 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965516 | 0.86 | G6PD (0.54) | BCHEACHEG6PDSMN1; SMN2HSD17B10 | |
| SCHEMBL17718253 | 0.85 | ACHE (0.57) | BCHEACHEG6PDLMNA | |
| SCHEMBL17722483 | 0.82 | BCHE (0.64) | BCHEACHEG6PDMEN1KMT2A | |
| SCHEMBL6966154 | 0.81 | BCHE (0.66) | BCHEACHEG6PDMEN1KMT2A | |
| SCHEMBL11291599 | 0.79 | BCHE (0.62) | BCHEACHEG6PDSMN1; SMN2MEN1 | |
| SCHEMBL6964455 | 0.78 | BCHE (0.54) | BCHEACHEG6PDMEN1KMT2A | |
| SCHEMBL17710447 | 0.75 | BCHE (0.63) | BCHEACHEG6PD | |
| SCHEMBL11607679 | 0.74 | BCHE (1.00) | BCHEACHEG6PDMEN1KMT2A | |
| SCHEMBL29965637 | 0.73 | ALDH1A1 (0.55) | SMN1; SMN2HSD17B10KMT2APTGER1POLB | |
| SCHEMBL28543149 | 0.73 | HPGD (0.58) | SMN1; SMN2HSD17B10KMT2AHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729465-B1 | PYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE DAVIS & CO (US) | 2003-01-22 | — | — | EP | disclosed |
| US-6005103-A | TREATMENT OF BACTERIAL AND VIRAL INFECTIONS AND DISEASES, INCLUDING AIDS | WARNER-LAMBERT COMPANY (US) | 1999-12-21 | — | — | US | disclosed |
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |