Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | FCER2 | P06734 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1616351 | 0.86 | MEN1 (0.56) | MEN1KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL4976068 | 0.86 | MEN1 (0.56) | MEN1KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL17722006 | 0.84 | REN (0.48) | MEN1KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL338918 | 0.83 | MMP8 (0.54) | MEN1KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL5866871 | 0.80 | ALDH1A1 (0.71) | MEN1KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL3872511 | 0.76 | KMT2A (0.55) | MEN1KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL2299158 | 0.76 | MEN1 (0.55) | MEN1KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL5907663 | 0.76 | MEN1 (0.65) | MEN1KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL21233937 | 0.76 | MEN1 (0.65) | MEN1KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL4191585 | 0.76 | HPGD (0.52) | MEN1KMT2AHPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422230-B2 | Process for the preparation of an anticonvulsant agent pregabalin hydrochloride | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-08-23 | — | — | US | disclosed |
| US-20160122289-A1 | PROCESS FOR THE PREPARATION OF AN ANTICONVULSANT AGENT PREGABALIN HYDROCHLORIDE | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160122289-A1 | PROCESS FOR THE PREPARATION OF AN ANTICONVULSANT AGENT PREGABALIN HYDROCHLORIDE | GABRE, GABRG1, GABRB2 | MEN1 2485/4885KMT2A 2396/4885HPGD 718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.