Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CD44 | P16070 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL545054 | 0.81 | MAPT (0.47) | ALDH1A1TDP1GAAMAPTMEN1 | |
| SCHEMBL4097610 | 0.80 | ALDH1A1 (0.46) | TSHRCYP3A4ALDH1A1TDP1ADRA2B | |
| SCHEMBL8174091 | 0.73 | CYP3A4 (0.62) | TSHRCYP3A4PIK3CAALDH1A1TDP1 | |
| SCHEMBL907658 | 0.73 | ACHE (0.61) | TSHRCYP3A4PIK3CAALDH1A1TDP1 | |
| SCHEMBL176878 | 0.73 | TDP1 (0.56) | TSHRALDH1A1TDP1GAAHSD17B10 | |
| SCHEMBL176880 | 0.73 | TDP1 (0.56) | TSHRALDH1A1TDP1GAAHSD17B10 | |
| SCHEMBL30716857 | 0.73 | CA1 (0.35) | TSHRALDH1A1TDP1PTGS1GAA | |
| SCHEMBL4451596 | 0.72 | TSHR (0.41) | TSHRTDP1ACHEMAPTKDM4E | |
| SCHEMBL13394018 | 0.71 | CYP3A4 (0.59) | TSHRCYP3A4PIK3CAALDH1A1TDP1 | |
| SCHEMBL265737 | 0.71 | ALDH1A1 (0.62) | TSHRCYP3A4PIK3CAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110251418-A1 | CASR AGONISTS | AJINOMOTO CO., INC. (JP) | 2011-10-13 | — | — | US | disclosed |
| EP-2345636-A1 | CASR AGONIST | Ajinomoto Co., Inc. (JP) | 2011-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251418-A1 | CASR AGONISTS | CASR, GIPR, GRIK5 | TSHR 481/4885CYP3A4 3376/4885PIK3CA 1043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.