SCHEMBL265737

SCHEMBL265737

COc1cccc(N)c1C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.62
TDP1 Q9NUW8 2/20 0.62
ADRA2B P18089 1/20 0.62
PTGS1 P23219 1/20 0.62
CYP3A4 P08684 4/20 0.59
TSHR P16473 2/20 0.59
PIK3CA P42336 1/20 0.59
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA4 P22748 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
KDM4E B2RXH2 2/20 0.44
LMNA P02545 2/20 0.44
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.44
POLB P06746 1/20 0.44
BLM P54132 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30258790 1.00 ALDH1A1 (0.62) ALDH1A1TDP1ADRA2BPTGS1CYP3A4
Hydrochloric Acid SCHEMBL312522 0.98 ALDH1A1 (0.60) ALDH1A1TDP1ADRA2BPTGS1CYP3A4
SCHEMBL23888255 0.85 ALDH1A1 (0.56) ALDH1A1TDP1ADRA2BPTGS1CYP3A4
SCHEMBL30178244 0.85 ALDH1A1 (0.56) ALDH1A1TDP1ADRA2BPTGS1CYP3A4
SCHEMBL8174091 0.83 CYP3A4 (0.62) ALDH1A1TDP1ADRA2BPTGS1CYP3A4
SCHEMBL146841 0.82 CA1 (0.61) ALDH1A1TDP1ADRA2BPTGS1CYP3A4
SCHEMBL18550731 0.81 ALDH1A1 (0.57) ALDH1A1TDP1ADRA2BPTGS1CYP3A4
SCHEMBL5159608 0.81 TDP1 (0.57) ALDH1A1TDP1ADRA2BPTGS1TSHR
SCHEMBL13394018 0.81 CYP3A4 (0.59) ALDH1A1TDP1ADRA2BPTGS1CYP3A4
SCHEMBL6289998 0.79 CYP3A4 (0.56) ALDH1A1TDP1ADRA2BPTGS1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 692 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9249091-B2 Post-treated sulfurized salt of an alkyl-substituted hydroxyaromatic composition CHEVRON ORONITE COMPANY LLC (US) 2016-02-02 US claimed
US-20130165359-A1 POST-TREATED SULFURIZED SALT OF AN ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOSITION CHEVRON ORONITE COMPANY LLC (US) 2013-06-27 US claimed
US-8288552-B2 Dihydropyridone amidesas P2X7 modulators ROCHE PALO ALTO LLC (US) 2012-10-16 US claimed
US-7056986-B2 ethylene monomer can be a vinyl ketone, ether, ester, halide, nitrile, aromatic, or an allyl ether; acrylic monomer can be a mono- or diacid or monoester of a diacid; a monoamine, a guanidine compound, and an aromatic diamine; improved vulcanizability, balance between processability and compression set DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2006-06-06 US claimed
CN-122055368-A PKMYT1 inhibiting compounds and uses thereof 杭州中美华东制药有限公司 2026-05-15 CN disclosed
EP-4126879-B1 N-PHENYL SUBSTITUTED INDOLE DERIVATIVES AS MYT1 INHIBITORS FOR THE TREATMENT OF CANCER REPARE THERAPEUTICS INC (CA) 2026-01-21 EP disclosed
US-20250346593-A1 IMIDAZO(1,2-1)PYRIDINE DERIVATIVES AS RIPK2 INHIBITORS INTERLINE THERAPEUTICS INC (US) 2025-11-13 US disclosed
US-12433826-B2 Primer and kit of primer and dental material KETTENBACH GMBH & CO. KG (DE) 2025-10-07 US disclosed
US-12435090-B2 Compounds, pharmaceutical compositions, and methods of preparing compounds and of their use REPARE THERAPEUTICS INC. (CA) 2025-10-07 US disclosed
WO-2025077716-A1 PKMYT1 INHIBITORY COMPOUND AND USE THEREOF 杭州中美华东制药有限公司 2025-04-17 WO disclosed
CN-119698416-A Imidazo (1, 2-A) pyridine derivatives as RIPK2 inhibitors 英特莱治疗公司 2025-03-25 CN disclosed
EP-4524139-A1 IMIDAZOPYRIDAZINE SUBSTITUTED BENZENE RING DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE Shanghai Simr Biotechnology Co., Ltd. (CN) 2025-03-19 EP disclosed
US-4762644-A AROMATIC POLYAMINE WITH ANIONICDOPES SHOWA DENKO KABUSHIKI KAISHA (JP) 1988-08-09 US disclosed
EP-0214310-A1 CONDUCTIVE POLYMER SOLUTION AND PROCESS FOR PRODUCING CONDUCTIVE ARTICLES FROM THE SOLUTION SHOWA DENKO KABUSHIKI KAISHA (JP) 1987-03-18 EP disclosed
EP-0038458-B1 4-HYDROXY-1,2-BENZISOTHIAZOL-3(2H)-ONE-1,1-DIOXIDE, THEIR SALTS, THEIR PREPARATION AND THEIR UTILIZATION Dr. Karl Thomae GmbH (DE) 1983-09-21 EP disclosed
US-4404230-A ARTICIFIAL SWEETENERS DR. KARL THOMAE GMBH (DE) 1983-09-13 US disclosed
EP-0038458-A1 4-Hydroxy-1,2-benzisothiazol-3(2H)-one-1,1-dioxide, their salts, their preparation and their utilization Dr. Karl Thomae GmbH (DE) 1981-10-28 EP disclosed
US-4058642-A HYPERTENSIVE BOEHRINGER INGELHEIM GMBH (DT) 1977-11-15 US disclosed
US-3997548-A INSECTICIDE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1976-12-14 US disclosed
US-3954997-A MITICIDES, INSECTICIDES THE UPJOHN COMPANY (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12433826-B2 Primer and kit of primer and dental material MVD, KIT, POLL ALDH1A1 337/4885TDP1 1732/4885ADRA2B 4284/4885
US-20250346593-A1 IMIDAZO(1,2-1)PYRIDINE DERIVATIVES AS RIPK2 INHIBITORS RIPK2, RIPK1, RIPK4 ALDH1A1 3792/4885TDP1 938/4885ADRA2B 4228/4885
US-20130165359-A1 POST-TREATED SULFURIZED SALT OF AN ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOSITION TST, PAH, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 ALDH1A1 814/4885TDP1 1379/4885ADRA2B 541/4885
US-12435090-B2 Compounds, pharmaceutical compositions, and methods of preparing compounds and of their use PLK1, CSNK1A1, CSNK1G1 ALDH1A1 4093/4885TDP1 677/4885ADRA2B 3145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.