Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | AGXT | P21549 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16771868 | 0.80 | CYP11B2 (0.50) | KIF11PARP1PARP3CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL16760250 | 0.79 | CYP11B2 (0.49) | KIF11PARP1PARP3CYP3A4ALDH1A1 | |
| SCHEMBL16211576 | 0.77 | TSHR (0.52) | DPP4CYP3A4TSHRMAPK1HTR2C | |
| SCHEMBL16654724 | 0.75 | GRIN2B (0.36) | MAOBPARP1PARP3CYP3A4ALDH1A1 | |
| SCHEMBL30161845 | 0.74 | NT5E (0.37) | CYP3A4TSHRMAPK1 | |
| SCHEMBL29005375 | 0.74 | SMN1; SMN2 (0.36) | KIF11TAAR1CYP3A4ALDH1A1TSHR | |
| SCHEMBL16760268 | 0.74 | NT5E (0.37) | CYP3A4TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL21995396 | 0.72 | NT5E (0.36) | CYP3A4TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL30161934 | 0.72 | NT5E (0.36) | CYP3A4TSHRMAPK1 | |
| SCHEMBL30936094 | 0.69 | AHR (0.70) | CYP3A4ALDH1A1TSHRMAPK1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170320848-A1 | COMPOUNDS FOR USE IN ANTHELMINTHIC TREATMENT | BAYER ANIMAL HEALTH GMBH (DE) | 2017-11-09 | — | — | US | disclosed |
| US-20170320848-A1 | COMPOUNDS FOR USE IN ANTHELMINTHIC TREATMENT | BAYER ANIMAL HEALTH GMBH (DE) | 2017-11-09 | — | — | US | disclosed |
| US-20170320848-A1 | COMPOUNDS FOR USE IN ANTHELMINTHIC TREATMENT | BAYER ANIMAL HEALTH GMBH (DE) | 2017-11-09 | — | — | US | disclosed |
| EP-3212612-A1 | COMPOUNDS FOR USE IN ANTHELMINTHIC TREATMENT | Bayer Animal Health GmbH (DE) | 2017-09-06 | — | — | EP | disclosed |
| WO-2016066574-A1 | COMPOUNDS FOR USE IN ANTHELMINTHIC TREATMENT | BAYER ANIMAL HEALTH GMBH (DE) | 2016-05-06 | — | — | WO | disclosed |
| WO-2016066574-A1 | COMPOUNDS FOR USE IN ANTHELMINTHIC TREATMENT | BAYER ANIMAL HEALTH GMBH (DE) | 2016-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170320848-A1 | COMPOUNDS FOR USE IN ANTHELMINTHIC TREATMENT | ACHE, COX5B, TUBB6 | KIF11 3922/4885MAOB 519/4885TAAR1 3803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.